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Intra-Cellular

Regional leaders seem like a mix of good and bad. But the worst micromanagement in this industry always starts at the top. So the real question is what is the mentality of top management above the Salesforce? It's a bit of a roll of the dice with a new company, there is no track record, and the pressure for revenue is on. Could end up horrible, could end up great and rewarding. Only time will tell.

Welcome to the glorious world of start ups. They are perfect when you are without a job (or losing one soon) Otherwise they are always a high risk /high reward gamble. Theres a little more certainty if you are following former colleagues.
Its just the nature of the beast.
 




Welcome to the glorious world of start ups. They are perfect when you are without a job (or losing one soon) Otherwise they are always a high risk /high reward gamble. Theres a little more certainty if you are following former colleagues.
Its just the nature of the beast.

Completely agree. For me Intracellular didn't offer enough to make the risk worth it. For people who took the position, I hope they did.
 




Based on the reduction in the PANSS scores in the studies, this is a mediocre medication at best. The high percentage of sedation is also not positive.

That’s right. It’s going to be a very tough sell. The sedation will be a problem. The lower EPS may help a few patients more, but the vast majority of patients never experience severe EPS, or even bad enough to switch to another product. As usual, the managed care coverage will be the biggest problem of all.
 




When it gets closer to 1/15, I’m going to ask for more money. I don’t think they’ve considered most of us will be getting some sort of merit increase by March.
If they just don’t care about the lower than promised offers, there will be several backing out. Also what about the 2nd hiring wave that they will be in a hurry to complete? Lower than $130k just wont net the type of experience they need.

Most experienced reps at Otsuka, Janssen and Alkermes are not making more than $130k. Don't let
anyone here fool you with that BS. This is psychiatry, not oncology. Any dumbass can sell in psychiatry.
Just look at the people in the 3 companies I mentioned.
 








Most experienced reps at Otsuka, Janssen and Alkermes are not making more than $130k. Don't let
anyone here fool you with that BS. This is psychiatry, not oncology. Any dumbass can sell in psychiatry.
Just look at the people in the 3 companies I mentioned.

Honestly, reps I know in psych are in the 115 - 145 range, average probably being 130, possibly slightly less.
 




That’s right. It’s going to be a very tough sell. The sedation will be a problem. The lower EPS may help a few patients more, but the vast majority of patients never experience severe EPS, or even bad enough to switch to another product. As usual, the managed care coverage will be the biggest problem of all.

Sedation an issue for Schizophrenia? I don't think so. Most providers want to knock these patients out, look how well the sedating meds have done. I think the bigger issue is what looks like questionable positive symptoms efficacy.

Be interesting to see how this goes real world.
 




Most experienced reps at Otsuka, Janssen and Alkermes are not making more than $130k. Don't let
anyone here fool you with that BS. This is psychiatry, not oncology. Any dumbass can sell in psychiatry.
Just look at the people in the 3 companies I mentioned.

Oncology is a joke. At least there is still selling happening in psych. You actually have to leave the house in psych, oncology reps are sitting home waiting for their monthly lunch
 




Will Medicaid cover this drug? That’s the question. With the majority of patients covered on state Medicaid plans...what’s ITC’s strategy? I know my state waits a year to even consider a new to market drug.
 




Will Medicaid cover this drug? That’s the question. With the majority of patients covered on state Medicaid plans...what’s ITC’s strategy? I know my state waits a year to even consider a new to market drug.

Hopefully there isn't too much pressure on "underperforming" reps. The real shame is when a company compares reps in completely different landscapes. Make no mistake, the pressure will be on to drive revenue. This company has done nothing but spend at this point.
 




Based on the reduction in the PANSS scores in the studies, this is a mediocre medication at best. The high percentage of sedation is also not positive.

you think schizophrenia is the target here? Really?
Of the branded market, who’s talking Schiz? Anyone? Not even Vanda with Fanapt and that’s their only indication. They’re off label with anxiety. Allergen - every patient is bipolar. Sunovion- they’ll take what they get. Otsuka- PTSD and anxiety.

the real push early is relationships and then bipolar into MDD. CMHC’s, beholdin to Medicaid, stay with the cheap stuff. Period

and funny you think sedation is bad. Quetiapine has done a multi-million dollar business on sedation alone.
 




you think schizophrenia is the target here? Really?
Of the branded market, who’s talking Schiz? Anyone? Not even Vanda with Fanapt and that’s their only indication. They’re off label with anxiety. Allergen - every patient is bipolar. Sunovion- they’ll take what they get. Otsuka- PTSD and anxiety.

the real push early is relationships and then bipolar into MDD. CMHC’s, beholdin to Medicaid, stay with the cheap stuff. Period

and funny you think sedation is bad. Quetiapine has done a multi-million dollar business on sedation alone.

I am on board and hope all works out but let's be honest here. These other indications are far from a sure thing. Didn't one of the bipolar depression studies fail?
 




you think schizophrenia is the target here? Really?
Of the branded market, who’s talking Schiz? Anyone? Not even Vanda with Fanapt and that’s their only indication. They’re off label with anxiety. Allergen - every patient is bipolar. Sunovion- they’ll take what they get. Otsuka- PTSD and anxiety.

the real push early is relationships and then bipolar into MDD. CMHC’s, beholdin to Medicaid, stay with the cheap stuff. Period

and funny you think sedation is bad. Quetiapine has done a multi-million dollar business on sedation alone.

Very sad, but all of this is true. Did you see what happened to Sage after the summer-long PR campaign?
Yikes.

Schizophrenia gets you in front of prescribers out of curiosity. Secondary indications, if they come, will be the revenue.
 




It’s pretty obvious the managers had their “own people” they wanted to bring over. Even reps with very little to no psychiatry experience. It’s basically old Forest labs made up all over again - good old boy network. Just watch- b&c target payout will be low, tons of sample dropping and hard AF managed care coverage with plenty of metric check the boxes...

as for clinical data, it didn’t look that great. Look at it online if you don’t believe me. I believe it will do ok but by no means a blockbuster The efficacy was decent but again not a home run where providers are going to jump on it. It’ll be the train wreck patient who isn’t compliant and it’ll stay around a 1% market share- then in say 3-5 years the company will have a hostile take over or ceo will sell.
And anyone working for dragon I mean degan, better get on his board of micro managing or hope off the train
 












For those of you already hired in Round one, any feedback re ability to negotiate anything - salary, vacation, new hire bonus. I’m in round two. Thanks.

For myself and everyone I know who got an offer, all told no negotiation of any sort. They've lost some really top tier reps over not having the flexibility to sweeten the pot.
 








I had an opportunity to throw my hat in the ring for one of these openings, but I ultimately decided to sit this one out. Coming to market with only a schizophrenia indication relegates much of your selling to community mental health clinics, as mentioned above. A novel mechanism will certainly raise some eyebrows but the majority of the end users are not being treated in a private practice setting and are a heavily subsidized patient population. In my state, all of the managed medicaid plans require a minimum of two generic atypicals before they will even consider covering a branded agent with a prior auth. In that regard, Caplyta will just be the next branded agent on the non-preferred list. An additional indication for bipolar is the game-changer. Unless you are going to sell this product with a wink and a nod to private psychs under the umbrella of “class effect” efficacy in bipolar folks....it’s going to be a bit of a slog in the early stages of launch. Best wishes to you anyway.
 




I had an opportunity to throw my hat in the ring for one of these openings, but I ultimately decided to sit this one out. Coming to market with only a schizophrenia indication relegates much of your selling to community mental health clinics, as mentioned above. A novel mechanism will certainly raise some eyebrows but the majority of the end users are not being treated in a private practice setting and are a heavily subsidized patient population. In my state, all of the managed medicaid plans require a minimum of two generic atypicals before they will even consider covering a branded agent with a prior auth. In that regard, Caplyta will just be the next branded agent on the non-preferred list. An additional indication for bipolar is the game-changer. Unless you are going to sell this product with a wink and a nod to private psychs under the umbrella of “class effect” efficacy in bipolar folks....it’s going to be a bit of a slog in the early stages of launch. Best wishes to you anyway.

Only two failures? Consider yourself lucky.

But yes, this launch will be a real heavy lift in many geographies. Hopefully they got the best of the best when in comes to reps in those areas.