From a senior, now retired, ex-sales exec, originally with Stuart/ICI/Zeneca and unfortunately, and finally, AZ.
The changes started when the industry was first required to hire females. These new reps were clearly as good as the males were when fully trained and weathered. But a strange thing happened, and the industry took notice. The females tended to change companies very quickly and needed constant replacement. Newbies (females) were hired as replacements after a year or two, but not at higher salaries as in the past. The industry had discovered the "glass ceiling" as a means of keeping all future salaries down. The stature of the reps was overall changed, particularly as seniority began to disappear.
Within some years other major changes took place. Television and print media was discovered by big pharma, and the TV evening news prospered greatly, but the salesforces had to pay for the media promotions. Therefore, things really began to change. Bonus's were lowered, pressure was applied to the reps.... higher call averages, individuality became passe as the computer took over and the parameters determining sales values became predominant over personal skills and individual value to the company. People became numbers, even more so as the sales forces became immense in numbers, became less skilled in salesmanship, and generally robotic in nature.
As time passed marketing over-powered sales and the heart and soul of the indusrtry virtually collapsed with many of the big name companies merging or failing (including AZ); pharma became the land of "me-toos" and shrinking sales forces. The senior reps were leaving out of disgust or frustration, and the kids found that they had really no where to go, especially as the economy began to falter.
I'm not being specific to AZ, because you all know the management and HR problems that have now existed for well over ten years, with still no blue sky in the forecast. Whether AZ will even eventually survive is definitely in question.
Will the industry survive? Probably, but not as you know it. It will get much more technical with time, and sales will be much more attuned to groups, hospitals, and research....and probably eliminating mass sales and marketing as we know it now. Only the best will survive, and it could get really ugly out there in the next ten or so years.
I wish you all the best for the future, but I'm happy as hell to be out of there. It's an ugly picture!