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patient deaths
Astellas Sees Path Forward for Gene Therapy Despite Four Patient Deaths
Astellas Sees Path Forward for Gene Therapy Despite Four Patient Deaths
BioSpace
Astellas
AT132
patient deaths
FDA
X-linked myotubular myopathy
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ESMO: AstraZeneca-Daiichi get clarity on patient deaths for Enhertu follow up Dato-DXd, survival data still unclear
ESMO: AstraZeneca-Daiichi get clarity on patient deaths for Enhertu follow up Dato-DXd, survival data still unclear
Fierce Biotech
ESMO
Daiichi Sankyo
AstraZeneca
Enhertu
patient deaths
clinical trials
non-small cell lung cancer
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Patient Death Likely from Virus Used to Deliver Gene-Editing Therapy: NEJM Study
Patient Death Likely from Virus Used to Deliver Gene-Editing Therapy: NEJM Study
BioSpace
NEJM
clinical trials
Duchenne Muscular Dystrophy
patient deaths
Astellas
Pfizer
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FDA puts 2seventy CAR-T trial on hold in wake of patient death
FDA puts 2seventy CAR-T trial on hold in wake of patient death
Fierce Biotech
2seventy bio
clinical trials
FDA
patient deaths
AML
CAR-T
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Abiomed’s Impella Now Linked to 4 Deaths in Recent Recall
Abiomed’s Impella Now Linked to 4 Deaths in Recent Recall
Medical Devices and Diagnostics Industry
Medtech
Abiomed
JNJ
Impella
TAVR
patient deaths
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Regeneron rethinks CD28 bispecific R&D plan after 2 patients die
Regeneron rethinks CD28 bispecific R&D plan after 2 patients die
Fierce Biotech
Regeneron
prostate cancer
clinical trials
patient deaths
REGN5678
bispecific antibodies
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ADC Therapeutics Halts Enrollment of Zynlonta Trial After Seven Patient Deaths
ADC Therapeutics Halts Enrollment of Zynlonta Trial After Seven Patient Deaths
BioSpace
ADC Therapeutics
Zynlonta
clinical trials
patient deaths
diffuse large B-cell lymphoma
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DMD gene therapy death exposes risks of treating older patients
DMD gene therapy death exposes risks of treating older patients
Fierce Biotech
Cure Rare Disease
gene therapy
clinical trials
DMD
patient deaths
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AACR: Patient deaths taint Roche's industry-first early-stage liver cancer readout for Tecentriq and Avastin
AACR: Patient deaths taint Roche's industry-first early-stage liver cancer readout for Tecentriq and Avastin
Fierce Pharma
Roche
AACR
liver cancer
patient deaths
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Patient death spurs trial halt for Magenta Therapeutics
Patient death spurs trial halt for Magenta Therapeutics
Endpoints
Magenta Therapeutics
MGTA-117
clinical trials
patient deaths
AML
myelodysplastic syndrome
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3rd patient death potentially tied to Eisai's Alzheimer's drug reported
3rd patient death potentially tied to Eisai's Alzheimer's drug reported
Fierce Biotech
Biogen
Eisai
Alzheimer's disease
clinical trials
patient deaths
lecanemab
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Only Patient in N-of-1 CRISPR Trial for Duchenne Muscular Dystrophy Dies
Only Patient in N-of-1 CRISPR Trial for Duchenne Muscular Dystrophy Dies
BioSpace
CRISPR
clinical trials
patient deaths
Duchenne Muscular Dystrophy
CRD-TMH-001
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Medtronic reports six more injuries, one additional death related to HVAD battery problems
Medtronic reports six more injuries, one additional death related to HVAD battery problems
Medtech Dive
Medtech
devices
Medtronic
patient deaths
HVAD pump
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Novartis reports deaths of two patients treated with Zolgensma gene therapy
Novartis reports deaths of two patients treated with Zolgensma gene therapy
BioPharma Dive
Novartis
gene therapy
Zolgensma
SMA
patient deaths
spinal muscular atrophy
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MacroGenics closes solid tumor clinical trial after 7 people die
MacroGenics closes solid tumor clinical trial after 7 people die
Fierce Biotech
clinical trials
Macrogenics
enoblituzumab
solid tumors
patient deaths
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Philips investigates reports of 1 death, 4 injuries potentially tied to ventilator recall
Philips investigates reports of 1 death, 4 injuries potentially tied to ventilator recall
Medtech Dive
Philips
devices
Medtech
patient deaths
device recalls
Respironics V60 ventilator
ventilators
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FDA puts Curis' leukemia trial on partial hold after patient death spurs review of muscle breakdown
FDA puts Curis' leukemia trial on partial hold after patient death spurs review of muscle breakdown
Fierce Biotech
Curis
FDA
clinical trials
patient deaths
emavusertib
acute myeloid leukemia
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Death in Alpine's Keytruda combo trial triggers clinical hold, raises specter of earlier tragedy
Death in Alpine's Keytruda combo trial triggers clinical hold, raises specter of earlier tragedy
Fierce Biotech
Alpine Immune Sciences
davoceticept
Merck
Keytruda
clinical trials
patient deaths
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FDA quickly follows a voluntary pause for CAR-T 2.0 with a clinical hold to investigate 2 patient deaths
FDA quickly follows a voluntary pause for CAR-T 2.0 with a clinical hold to investigate 2 patient deaths
Endpoints
Celyad
FDA
patient deaths
CAR-T
clinical holds
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Baxter warns of potential blockages in infusion pumps linked to 3 deaths
Baxter warns of potential blockages in infusion pumps linked to 3 deaths
Fierce Biotech
devices
Medtech
Baxter International
infusion pumps
patient deaths
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