Trulicity

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Anonymous said:
Well let us hope you aren't in pharma!

According to the PI out of 834 patients at the high dose:

175 of 834 patients experienced nausea.
100 of 834 experienced vomiting, which included retching, vomiting, projectile vomiting.
91 of 800+ experienced what was considered "severe" gastrointestinal side effects.

NO THANKYOU!!!

There are better choices available.
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Thank You. FINALLY some data...I would assume the lower dose has fewer issues, but less efficacy as well. Does anyone know what the rates are for the other GLP-1's ?
 












Anonymous said:
I would suggest that you don't be so smug, and stop minimizing tolerability issues.
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You are mistaking smugness for irritation. The same irritation at reps that ran around saying Lantus causes cancer, or januvia causes stevens johnson, or actos causes bone fracture, or farxiga causes bladder cancer. All the while implying whatever is in your bag is as pure as the driven snow.

I'm very aware of tolerability issues, personally getting to enjoy some with my ra med. Just because you found a footnote in a pi doesn't mean it will happen to everyone or even a majority. It doesn't mean it won't occur with others in the class. It also means that if it does occur, the benefit may outweigh the risk. It may also even occur once in what could be years of treatment. This will be a valuable medicine for many people, just as victoza, byetta, bydureon, and tanzeum are valuable.

Ultimately this will be decided by a patient and their hcp, and insurance provider, I guess. I'm sure we will all know the answer in the months to come. Best of luck to you!
 










































Look, let's be honest. Access sucks, and will remain p/a or Tier 3 for many quarters... so until then the conversation unfortunately will remain focused around the benefit to risk eg nausea. Let's at least be honest and prepare for that conversation.
 






Anonymous said:
Look, let's be honest. Access sucks, and will remain p/a or Tier 3 for many quarters... so until then the conversation unfortunately will remain focused around the benefit to risk eg nausea. Let's at least be honest and prepare for that conversation.
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Ok let me put my Kool Aid down, there..the drug sucks Ok.
 






Anonymous said:
Look, let's be honest. Access sucks, and will remain p/a or Tier 3 for many quarters... so until then the conversation unfortunately will remain focused around the benefit to risk eg nausea. Let's at least be honest and prepare for that conversation.
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Let's be honest, Lilly is a poor negotiator when it comes to getting on formularies!! We can't even bump out Byetta/Bydureon and we have superior efficacy compared to Byetta and don't cause the nodules of Bydureon!!! Hmmmm...... Comparable efficacy to Victoza and 85% less injections!!!! You Fu__ing SUCK Lilly!
 






Anonymous said:
Let's be honest, Lilly is a poor negotiator when it comes to getting on formularies!! We can't even bump out Byetta/Bydureon and we have superior efficacy compared to Byetta and don't cause the nodules of Bydureon!!! Hmmmm...... Comparable efficacy to Victoza and 85% less injections!!!! You Fu__ing SUCK Lilly![/QUOTE



Let's say the drug is excellent, Lilly has lost the ability to market it correctly if it ever had the ability. Marketing/ Brand teams have always been a very weak point at Lilly. Remember the yard sticks for Cialis ? Is that the best you got ?
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Anonymous said:
Let's be honest, Lilly is a poor negotiator when it comes to getting on formularies!! We can't even bump out Byetta/Bydureon and we have superior efficacy compared to Byetta and don't cause the nodules of Bydureon!!! Hmmmm...... Comparable efficacy to Victoza and 85% less injections!!!! You Fu__ing SUCK Lilly!
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Lilly will NEVER be the diabetes leader in 2020 until we negotiate to get on formularies! We've been selling Trulicity for 5 months! We should have been on more formularies by now! Also, I can't think of one Medicare Plan that Trulicity is on in our Area!! Come on Lilly, start kicking Novo's butt to get on formularies!!!! We've been downhill since 2004 and haven't been able to crawl our way out!! I've been approached by my Novo reps to fill an open position and I am considering it! Much better pay and bonuses, they pay for Internet, cell phone, and MUCH less is paid for monthly use of the company car!
 






Anonymous said:
Let's be honest, Lilly is a poor negotiator when it comes to getting on formularies!! We can't even bump out Byetta/Bydureon and we have superior efficacy compared to Byetta and don't cause the nodules of Bydureon!!! Hmmmm...... Comparable efficacy to Victoza and 85% less injections!!!! You Fu__ing SUCK Lilly!
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Because we are too busy borrowing money to pump up the stock price for top dogs' bonuses
 






All kidding aside. We have a good product that is efficacious. However every time I get a script generated, nurses are telling me they get call backs with the nausea. Our device is awesome, but a news flash to marketing, it's what comes out of the device that keeps patients coming back . I know how to sell, but at this rate, I will need 100 nrx's to keep 10 TRX's.
 






Anonymous said:
All kidding aside. We have a good product that is efficacious. However every time I get a script generated, nurses are telling me they get call backs with the nausea. Our device is awesome, but a news flash to marketing, it's what comes out of the device that keeps patients coming back . I know how to sell, but at this rate, I will need 100 nrx's to keep 10 TRX's.
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It's even more for Forteo then even they eventually disappear
 












Anonymous said:
Lilly will NEVER be the diabetes leader in 2020 until we negotiate to get on formularies! We've been selling Trulicity for 5 months! We should have been on more formularies by now! Also, I can't think of one Medicare Plan that Trulicity is on in our Area!! Come on Lilly, start kicking Novo's butt to get on formularies!!!! We've been downhill since 2004 and haven't been able to crawl our way out!! I've been approached by my Novo reps to fill an open position and I am considering it! Much better pay and bonuses, they pay for Internet, cell phone, and MUCH less is paid for monthly use of the company car!
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Your job is to sell, regardless of what the formulary coverage is. Quit asking someone else to do your job for you. Lilly isn't willing to give this drug away so that you can cut out at 2pm every day and have the formulary drive usage. Go do your job and let the big boys worry about big business decisions.
 






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