Trulicity

I'm not a sales rep, just a patient. I received trulicity and took a shot 10 days ago. Nauseated all week. The 6th day past the shot, I puked all day and had explosive diarrhea for nearly 24 hours. This is the 10th day, and it's starting up again. First the diarrhea, now horrible belching and then comes the vomiting. I wish I had never injected this crap. I thought metformin was bad...
 






I'm not a sales rep, just a patient. I received trulicity and took a shot 10 days ago. Nauseated all week. The 6th day past the shot, I puked all day and had explosive diarrhea for nearly 24 hours. This is the 10th day, and it's starting up again. First the diarrhea, now horrible belching and then comes the vomiting. I wish I had never injected this crap. I thought metformin was bad...

Please tell your doctor about your experience...might save another patient from going through this!!
 






Type 2 who's been on Byetta / Bydureon since 2007. I can tell you the Bydureon injection _sucks_. Hurts like getting blood drawn every week, plus 5-10 minutes of tapping and sloshing to get the powder into suspension. Annoying the point that I've thought about going back to the 2x daily Byetta pen, but I do get significantly better control with the weekly, and I do a lot of business travel and dealing with the pen, avoiding heat (I'm sometimes in tropical countries) and needing to shoot myself up at specific times is a hassle. But shooting up with sticky syrup through a 23 gauge needle, not to mention being covered with nodules, also sucks.

On delivery, I'd imagine a heck of a lot of Bydureon users would jump for something better -- and "better" is a low bar.

On the other hand, projectile vomiting does not make for a good business meeting....

Was actually going to get a Trulicity scrip at my endo appt this month, but what I'm reading here and elsewhere about much worse GI side effects than exenatide or Victoza has given me pause. Will have to do more research on this. Crap, I was really hopeful.

5-10 minutes? You're waiting too long. It can be well mixed and injected in under a minute. At that time frame it looks pretty much like water coming out of the needed. The longer you wait, the thicker it gets - so don't wait.
 






I would really like to know about the nausea issue. Disclosure: I am not a troll, but someone who works in the GLP-1 field. I do know that all GLP-1 agonists(Byetta, Victoza) cause nausea in some patients. At least with Byetta, this gradually diminishes as the patients develop tolerance to the emetic effect. Trulicity is new and I am wondering if the nausea/vomiting is any worse or prolonged than with say, Byetta or Victoza? I think people working in sales would probably have a very good idea from physician feedback if this is a real concern. Again, not a Novo troll, just someone interested from a scientific standpoint. Thanks
 






I am a type two. I have been on both Victroza, then switch to Trulicity. May as well have been injecting water. No side effects, A1c actually went up. $750 for the drug ($50 co pay). It trash
 






Not really buying these “patient testimonials” being offered here ... quite unusual since 99% of posters at the site are Pharma sales personnel (admittedly, most are childish). Suspecting some kind of product smear campaign by a couple individuals because if Trulicity side effect profile was as severe (or prevalent) as described, this drug would never have achieved its current sales volume.