Most of the Genentech crew left because they realized quickly that the Novartis leadership on both the sales side as well as the reimbursement side were incompetent. I came over from Genentech with years of buy and bill on several different products and quickly realized Novartis didn’t ’get it’ and was unwilling to listen. Glad I took the severance as soon as it was offered to me.
Ultimately, it comes down to incompetence at the highest levels who are chicken shit to have open discussions and learn. They thought others couldn’t see how lost they were but it was obvious due to their unwillingness to discuss the business and how things could be improved.
Get out of the toxic CV franchise as fast as you can because you all know there are much better run companies that will pay for talent. Don’t let the pain of change keep you from leaving. It took a lot of effort and incompetence at the upper leadership level to have such an epic failure with Leqvio.