So what happens to CRM? The Leqvio launch has been a colossal disaster worth close to 10 billion. Do you release a large part of a sales force in the middle of an unsuccessful launch, or try to move forward at a snails pace and never recoup your investment? PCP needs to go, and the ISS team is past their due date. I’m certain Novartis has some company looking at geographic locations of where reps live in relation to their territory. Either way, you need to have some sort of plan in place. Good luck to everyone.