Frankly, I met incredibly talented scientists at NIBR, with insight and farsightedness. Many of the scientists are a million times better than the guys I have seen at e.g. Lilly and Abbott. For example Jeff Porter, Tewis Bouwemester, Chris Wilson, and in general most of the DMP people are absolutely outstanding. There are some idiots as well (whom I shall not name) but they are neutralized by the gret ones. Give them more time - research is tough and discoveries cannot be planned. My prediction is that great drugs will come about over time. And maybe a Nobel Prize as well.
I do have some concerns about NIBR though. The structures are too vertical, and the decisional power is too concentrated on the top. A bit more "subsidiarity" and empowerment of the middle layer might go a long way towards making happier coworkers and enhanced productivity. But these are quibbles - in general we are talking about a great powerhouse of science.