Yes, there will be layoffs.
Think about it this way, we cannot and have not supplanted our competitor TKI in RCC even though we are paired with the preferred PD1, have a much larger sales force when looking at the combined promotional effort of Merck and Eisai, and BMS's lack of support of Nivo/Cabo promotionally. We still trail them by a wide margin so what is the point of carrying the FTE's at the same level. We will layoff on our side and allow Merck to take their already bigger burden of promoting Len/Pem.
Couple that with A/B taking our share in 1L HCC and we are not beating Cabo in 2L post A/B...basically it shows our sales force is not doing a good enough job against our chief rival.