Lay-offs start December 1st - You heard it here first!

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Anonymous said:
Why do you always have to show your ignorance and resort to profanity???

I do not think the person was suggesting that Avandia was not getting the additional black box for Heart Attacks. Rather the article itself, as cited by the Wall Street Journal word for word, is lumping Avandia and Actos together again.

So why don't you send the Wall Street Journal a rebuttal and be sure to call them names too!!!
Click to expand...

No one was saying that the poster was denying a black box warning for Avandia, just that the poster seemed to be stating that it would effect Actos as well. The verbage of that article can be interpreted different ways. (1) That they were lumping the two together or (2) that they were just mentioning Actos as it is in the same class and had also recieved the CHF box.
 




Anonymous said:
This little bit of shattering news is going to add even more fuel to the fire as it will effect TPNA's bottom line - Watch and see, if I am not right in that Eli Lilly is a powerhouse and they will suck more $$$ out of your little arrangement with Actos. Don't say you did not see it coming when it happens!

http://208.101.7.228/boards/showthread.php?t=234303
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Is this supposed to make sense? I am not seeing any connection.
 




if you think your drug is safer than Avandia you are crazy or just plain stupid. I do not work for a pharmaceutical company, but I did research for FDA for the last 2 years in a small job. What I can tell you is both drugs pose a risk for MI's in the data being looked at. While I think the media is blowing the data out of proportion Actos showed similiar heart risks. HR-1.03.
Proactive was not a good study to compare because it did not meet primary end points and was compared to placebo. Avandia's "RECORD" was not the best data for Cardiovascular outcomes because it was an observational study.
Both your drugs will receive black box warnings for ischemic events. So if any of you think you are safer think again. You can beleive this post or ignore it, if you beleive it go out and get a new job, if not stay around and get laid off. Either way I mean you no harm just good luck.
 




OP here

I am so shocked that my little old handy work of just looking up a few things on the internet has actually inspired over 4,000 individual views of this post - Holy Shit!!!

It really did take less than a half an hour - and I was doing it for my own research and I think it wasn't wasted time whatsoever...This is my career and I want to be in the know of my future!

Whoever wrote the additional post right above this one is adding more incite and I appreciate it. I also think the post is kind to say what he/she did at the end by saying "Good Luck".

Just so you all know, I am a TPNAer. I know there will be at least three posts right after this one saying that I am a GSK troll or something to that effect, but I am sorry to disappoint you in the fact that I am what I said I am.

I still can't believe this thing has gotten over 4,000 hits. And THEY keep telling us not to go on Cafepharma - Yeah, okay...We'll get right on that one! (heh)
 




Maybe the OP knew something ahead of time???

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UPDATE 2-Takeda plunges on development woes

Tue Oct 30, 2007 7:04am EDT
Market News

More Business & Investing News...

By Edwina Gibbs

TOKYO, Oct 30 (Reuters) - Shares in Takeda Pharmaceutical Co Ltd (4502.T: Quote, Profile, Research) plunged 12 percent -- their biggest one-day fall in 20 years -- after U.S. authorities recommended it stop some trials of cholesterol-lowering TAK-475, one of its most promising drug candidates.

The surprise news led some analysts to cut their ratings on Japan's biggest drug maker and to slash or even eliminate the drug's potential earnings from their estimates for the company.

The U.S. Food and Drug Administration recommended Takeda halt trials with higher doses of the drug after elevated levels of an enzyme that may indicate liver damage were more often found than in control groups. This included severe cases of the complication.
 








[size=+2]Looks like GSK is trying to go with the Class Effect route in spinning this in the eyes of the doctors !!![/size]

UPDATE 2-US FDA adds heart warning to diabetes drug Avandia
Wed Nov 14, 2007 4:30pm EST
By Julie Vorman and Maggie Fox

WASHINGTON, Nov 14 (Reuters) - GlaxoSmithKline's Avandia will carry a "black box" warning that says the diabetes drug could cause chest pain or heart attacks, the U.S. Food and Drug Administration said on Wednesday.

The company will also start a trial comparing Avandia head to head with a rival drug, Takeda Pharmaceutical Co's Actos and perhaps other drugs, to see if the risk is unique to Avandia, the FDA said.

In the meantime, doctors should monitor patients closely for any heart effects, the FDA advised.
 




just shot by 5,000 views - imagine if I got 1 dollar for everyone of those hits??? okay now imagine if I did something really appealing and got 10 dollars for every hit??? Hmmmmmmm...maybe i am on to something here. :D

[size=+5]the power of the internet...can you feel it???[/size]
 




























[size=+3]...And so it begins to unravel[/size]

Takeda announce hiring freeze - November 21, 2007:eek:

There is a hiring freeze right now, and Cephlon is looking to cut. Does that mean Takeda might lose the co-promo w/Provigal? When does the co-promo contract end?
Click to expand...

Answer: Yes the contract is over with Cephalon - Provigil® went generic on November 22, 2007

Here look for yourself:

http://www.drugpatentwatch.com/innovation/



ps. To the idiot who wrote the question about the hiring freeze (in quotations above)...please learn how to spell Cephalon and Provigil® at the very least! I hope to God that you are not a Takeda employee. Geeze!
 




I'm trying to figure out what is the most comical about this thread.

1) The person who started it and the power and self satisfaction they feel by attempting to start panic anonymously through an internet message board. Way too much time on their hands and need to get a life.

OR

2) The people who are actually responding to him/her and believe the crap that's being posted.

Either way, I feel sorry for for both groups.

Anybody who doesn't use this website for anything other than entertainment value with a big smile on their face when reading posts is too stupid to have a job in this industry.
 




Anonymous said:
I'm trying to figure out what is the most comical about this thread.

1) The person who started it and the power and self satisfaction they feel by attempting to start panic anonymously through an internet message board. Way too much time on their hands and need to get a life.

OR

2) The people who are actually responding to him/her and believe the crap that's being posted.

Either way, I feel sorry for for both groups.

Anybody who doesn't use this website for anything other than entertainment value with a big smile on their face when reading posts is too stupid to have a job in this industry.
Click to expand...

Couldn't have said it better myself....except that I will comment on OP - obviously not a "TPNA'er", b/c we don't use terminology like that here - that comes from going to our tpna.com website, which makes this GSK rep even more pathetic. I want to know why s/he is holding on so hard - they've updated the risk in the Rosi label, there will be no removal of the class (as s/he predicted would happen NOV 15th), and s/he gets off on the fact that so many people viewed the post. Yeah, who wouldn't when you put a shock/awe statement on the subject line? Weird sense of satisfaction this person has...

Good luck in your future endeavors at GSK, if you are still there - I will enjoy selling the #1 prescribed Diabetic agent: ACTOS!
 




What is most comical about this thread is that although they are complaining, the last two posters are actively contributing to this thread's content.

Every new post brings more and more attention to this run away train of a thread. hee hee

It just proves how frightened everyone is about the welfare of Takeda TPNA, if indeed the unthinkable actually happens and it's buh-bye to Actos!!! ;)
 








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