Karyopharm - oncology

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anonymous said:
Here’s a list of what’s happened since he took over in 2021. It kind of makes you wonder what - if anything - the board would consider worthy of termination.

Share price down over 90%
Sales moribund/declining
Quarterly consensus estimates for sales or profit missed about half the time
Company removed from Russell 3000
Key development timeless missed
Pending nasdaq delisting because stock trades below $1
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Yep. Nothing to add.
 




anonymous said:
Yep. Nothing to add.
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What is even more annoying is we go through the motions like we are an established successful and sustainable company. We continue to spend money on worthless big pharma initiatives, development programs, unnecessary roles, and meetings. Let's all call it what it is and act accordingly, instead of pretending to be something we are never going to be.
 




anonymous said:
What is even more annoying is we go through the motions like we are an established successful and sustainable company. We continue to spend money on worthless big pharma initiatives, development programs, unnecessary roles, and meetings. Let's all call it what it is and act accordingly, instead of pretending to be something we are never going to be.
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Exaxtly
 












anonymous said:
What is even more annoying is we go through the motions like we are an established successful and sustainable company. We continue to spend money on worthless big pharma initiatives, development programs, unnecessary roles, and meetings. Let's all call it what it is and act accordingly, instead of pretending to be something we are never going to be.
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Yeah, this is like worrying constantly about getting that ceramic coating on your car’s finish. Meanwhile, the transmission is just about shot and the body is rusting out.
 




anonymous said:
What is even more annoying is we go through the motions like we are an established successful and sustainable company. We continue to spend money on worthless big pharma initiatives, development programs, unnecessary roles, and meetings. Let's all call it what it is and act accordingly, instead of pretending to be something we are never going to be.
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Agreed and it would be so simple and appreciated if they came out and said this:

"We know this is not the easiest drug to sell or company to work for, there have been massive amounts of turnover since you launched, the stock price is down significantly. We know this is not what you signed up for, and for those of you who have been here since launch, thank you for sticking it out. For those who have joined since, thank you for taking the risk and seeing it though. We know it doesn't always look like this is going to pay off but we are confident that there is a bright future here, if we can just hold on. Stick with it and as a sign of our commitment the C suite is taking a significant reduction in compensation and we will be diverting those funds to a meaningful retention bonus program to ensure that we keep top talent here as we enter into our next phase. Additionally, we are lessening the bureaucracy, and quite frankly the big pharma feel that we noticeable have slipped into. We will limit Zooms and in-person meetings to those that are absolutely necessary and from a results perspective we will cease to micromanage the bottle count day to day and take a long term view towards the success/failure of our product, and in plain langue stop freaking out. We will stop the "panic" every time an account is late in ordering or a treater doesn't have a patient ready go the same day another patient comes off the drug. We will be realistic. We will listen to you and put your insights into action. We know it hasn't gone as planned, we recognize that and we as an executive will do better".
 




anonymous said:
Agreed and it would be so simple and appreciated if they came out and said this:

"We know this is not the easiest drug to sell or company to work for, there have been massive amounts of turnover since you launched, the stock price is down significantly. We know this is not what you signed up for, and for those of you who have been here since launch, thank you for sticking it out. For those who have joined since, thank you for taking the risk and seeing it though. We know it doesn't always look like this is going to pay off but we are confident that there is a bright future here, if we can just hold on. Stick with it and as a sign of our commitment the C suite is taking a significant reduction in compensation and we will be diverting those funds to a meaningful retention bonus program to ensure that we keep top talent here as we enter into our next phase. Additionally, we are lessening the bureaucracy, and quite frankly the big pharma feel that we noticeable have slipped into. We will limit Zooms and in-person meetings to those that are absolutely necessary and from a results perspective we will cease to micromanage the bottle count day to day and take a long term view towards the success/failure of our product, and in plain langue stop freaking out. We will stop the "panic" every time an account is late in ordering or a treater doesn't have a patient ready go the same day another patient comes off the drug. We will be realistic. We will listen to you and put your insights into action. We know it hasn't gone as planned, we recognize that and we as an executive will do better".
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So many companies would benefit from saying that but no one ever says just weather the storm. This industry has turned into a nightmare and I am one of the lucky ones who chooses to work rather than having to work at these shit companies. Im bleeding it until it is dead.
 




anonymous said:
Agreed and it would be so simple and appreciated if they came out and said this:

"We know this is not the easiest drug to sell or company to work for, there have been massive amounts of turnover since you launched, the stock price is down significantly. We know this is not what you signed up for, and for those of you who have been here since launch, thank you for sticking it out. For those who have joined since, thank you for taking the risk and seeing it though. We know it doesn't always look like this is going to pay off but we are confident that there is a bright future here, if we can just hold on. Stick with it and as a sign of our commitment the C suite is taking a significant reduction in compensation and we will be diverting those funds to a meaningful retention bonus program to ensure that we keep top talent here as we enter into our next phase. Additionally, we are lessening the bureaucracy, and quite frankly the big pharma feel that we noticeable have slipped into. We will limit Zooms and in-person meetings to those that are absolutely necessary and from a results perspective we will cease to micromanage the bottle count day to day and take a long term view towards the success/failure of our product, and in plain langue stop freaking out. We will stop the "panic" every time an account is late in ordering or a treater doesn't have a patient ready go the same day another patient comes off the drug. We will be realistic. We will listen to you and put your insights into action. We know it hasn't gone as planned, we recognize that and we as an executive will do better".
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Clown
 




















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