The psychological mess behind all of the OB posts is quite interesting. I would even say entertaining, but I don't believe in taking pleasure in other people's misery and/or mental instability.
If my memory serves me right, HR has been in the same location for at least 3 years. They're email address hasn't changed either. Therefore, instead of passive-aggressively lashing out on a website, at what you believe to be a serious problem, try picking up the phone or writing to HR to explain your "case". IF you've already taken that route, then hire an attorney and leave Eisai. IF you CHOOSE to continue working here then you really have no right to complain.
I'm not quite sure what your definition of "hostile" is, but something tells me that you may not be cut out for this industry, or business in general. When goals aren't met (in any industry), every one from the top on down, feels the pressure. Some handle it better than others. If you are doing everything in your power, which includes giving 100% effort each and every day, then the pressure won't be felt as much. On the flip side, if your efforts are lacking, then yes, the pressure is far more intense.
If you want to know what a "hostile" environment is like, go work for any of the firms on Wall Street, and your days at Eisai will seem like a walk on the beach.
One more thing, let me guess...you think this is OB taking the time during the leadership meeting to respond to your posts. Now that's laughable!