Trifexis

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Anonymous said:
Right now, my 6-year old Corgi is dying at a nationally-acclaimed veterinary specialists clinic. Her liver is failing, in spite of heroic amounts of drug therapy during the last 72 hours. Neither the vet specialists nor the regular family vet believe there is any correlation between her having been on JUST TWO DOSES of Trifexis, and now her liver is failing.

We adopted her from a No-Kill group when she was 2 years old, knowing she had a light case of heartworms, with their advice to just keep her on heartworm preventative, and see how she did. If needed, we could put her through the heartworm cure, but we didn't have to put her through the extreme treatment immediately. The expectation was that the situation would not get worse, and it might get better. In fact, she's done fine with us for these four years and been a loved family pet. We've had 7 healthy pets over the years, and here she is the one dying of liver failure.

THE ONLY THING WE DID DIFFERENTLY THIS FALL is change her from two separate medicines of heartworm preventative and Comfortis to this one monthly tablet of Trifexis. And, she had only two doses of Trifexis in these last two months.

Maybe Trifexis is not the culprit. Maybe her liver was going to flame out over these two months anyway, but I will never use Trifexis again on any animal in my care.

DO NOT USE THIS MEDICINE. IT'S JUST NOT WORTH THE RISK TO YOUR PET. I suspect that my dog is just one more of the company's guinea pigs to locate the contraindications for the use of their medicine. If the nation's vets do not think it's a problem now, maybe a lot more dogs have to die to get their attention and force the company to take some precautions to warn dog owners that this product may not be suitable for some animals. The vet's techs had no such warnings when advising me that I could switch my dog over to Trifexis and save a few bucks. Two months on Trifexis, and now, after four good years, my dog is dying? I think it is far more than just a coincidence.
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Sorry to read about your pet. I read your post and checked my FDA label in my package of Trifexis. To avoid looking like a complete moron, you must not make such loud claims without first checking your facts. The label states that the manufacturer gave 17X dose over ten days and did not see any health risks with liver, kidneys, heart, brain, CNS, or anything else you care to make up. Again, sorry about your pet, but its not likely that a flea medication caused it.
 




We had a horrible experience and found MANY other dog owners reporting the same terrible reaction to this medication. We gave our 11 month blue tick coonhound a Trifexis tablet this Monday night. About 5 hours later, he was displaying the same symptoms that several of you mentioned. His eyes were rolling back into his head and he couldn’t focus on anything, he would look up at ceiling and open his mouth, try to sleep standing up and acted like a zombie! He couldn’t settle or sleep for awhile and was cold to the touch. He was shivering and when we flashed a bright flashlight he didn’t even flinch. We will NEVER give it to him again. It took 18 hours before he started acting normal again. Something needs to be done about that drug. We felt horrible for giving it to him. I have to wonder if it was poisoning him or affecting his brain the way it may do to the parasites it’s intended to treat. Here is the website we found similar experiences and we just added ours since it sure was a help at 3 a.m. when a vet wasn’t available by phone.
http://www.toypoodlerescue.net/inde...:trifexis-side-effects&catid=3:blog&Itemid=14
 




It has come to my attention that Vetsource has just signed a deal to provide the pharmacy filling for WagRx/Amazon.com

How do I get manufacturer contracts to buy direct and 10-20% under vet list costs and then turn around to sell to Amazon.com and it's owned entities?

Good job Novartis for that lucritive contract
 








People, if your pet has a problem or reaction to any product, report it to that manufacturer. Not cafepharma. This site is for whiners, sucky sales reps and a few unfortunate souls that stumble on to it.
 








Anonymous said:
I just got home from the vet. My dog had a terrible reaction to trifexis. Hives, extreme thirst, and very agitated. I spent the night trying to find something to give her relief. She spent the night sitting on my lap crying. She took comfortis and interceptor for over a year with not problem, two months ago my vet's office decided I needed to change her flea and heartworm medicine to trifexis. Today they refunded the full price of the trifexis and suggested I contact the company that makes trifexis and tell them of my dog's reaction. As you can see I'm not only telling them I'm telling anyone who will listen. I wonder what kind of a kick-back the vet's offices are getting to push this stuff when a dog is doing fine on their old medicine.
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My dog had an extremely bad reaction too. 2 hours after taking the drug she acted like she had drank a case of beer. She was breathing really hard and could barely stand up. She walked like she was really drunk. I called my Vet and they said it sounded like an allergic reaction and to give her Benedryl. After taking the large dosage of Benedryl she was still really agitated and it took 4 hours for her to go to sleep. They called the company and the Vet there confirmed that it was an adverse reaction to the drug.
 








Our two older goldens have been using Trifexis (tm) at the behest of our great vet, for five months. One gulps it down, the other needs to be coaxed, but also accepts it. We have observed no problems with either dog -- no seizures, no unusual hurling of food, no problems with annual blood sample. My wife and I are not pharma reps, primarily because we are not 23-year-old swimsuit models, but also because we have scruples (based on what we read here). Hope other readers have the same luck as we did. Oh, and we were Frontline Plus users for years, until both dogs developed a flea problem. Comfortis knocked it 100 percent out in less than four hours -- most of the fleas were dead in thirty minutes !
 








I am a consumer looking for information on a product and honest reviews. This place is 3 pages of grown children arguing about who's product is better. Jesus help all of you, life's gonna be tough!
 




Trifexis almost killed my 11 year old Daschund . After giving her the 6th dose she was acting strange.Starting with; looking very scared, shaking, very sensitive to the touch, not wanting to move, not eating or drinking. She could not walk on the 10th day. This drug should be recalled. I took her to the vet. And they did xrays which came out perfect. Blood work that showed liver problems. The vet perscribed denosyl to help with her liver, but the Trifexis is in her blood stream for 30 days . Nothing else I can do. (only hope she lives )
 




This attempt at a smear campaign against Trifexis is really sad! If you have questions about this or any product, talk to a vet please. God forbid you take the advice of this site.
 




It's not a smear campaign against Trifexis. Only a warning to save a dogs life. It was approved by the FDA Jan. 2011. Drug reactions unfortunately happen after they are approved. I am sure you have heard of drug recalls.
 
















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