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Time Capsule Predictions--Do not open until February 2016

If Frazier has been as dishonest with Merck as Obama has been in government, we are in for a rude awakening. Can't believe the lies and selective approach Obama takes to what is supposed to be law. I very much hope Frazier has not done such things at Merck but we never really know until it's too late.

Why does every board digress into some b!tch about Obama? Nothing really to do with Merck or these forums. Stick pins in your Obama voodoo doll if you want to do something productive.

So.... what you are predicting is that Obama will still be president February 2016.
 




Why does every board digress into some b!tch about Obama? Nothing really to do with Merck or these forums. Stick pins in your Obama voodoo doll if you want to do something productive.

So.... what you are predicting is that Obama will still be president February 2016.

Ouch...someone has Obama sensitivity syndrome.

2016 is Hilary vs. a Rubio/Christie/Cruz/Dowdy possibly plus a 3rd party candidate....

By then most working and retired Americans will be extremely upset with their very crumby and very expensive Obama healthcare. A new reformed approach will top the debate topics.....along with preventing total financial collapse that it may bring.
 








Ouch...someone has Obama sensitivity syndrome.

2016 is Hilary vs. a Rubio/Christie/Cruz/Dowdy possibly plus a 3rd party candidate....

By then most working and retired Americans will be extremely upset with their very crumby and very expensive Obama healthcare. A new reformed approach will top the debate topics.....along with preventing total financial collapse that it may bring.

Ouch...someone has a head-up-their-a$s syndrome. What the previous poster was trying to explain is that this is a Merck forum, not an "I'm an angry old white man who still cannot come to terms with Obama getting elected TWICE" forum. It's ok to hate Obama, but somehow it is entirely irrelevant to this entire forum. Focus: Merck.
 




Ouch...someone has a head-up-their-a$s syndrome. What the previous poster was trying to explain is that this is a Merck forum, not an "I'm an angry old white man who still cannot come to terms with Obama getting elected TWICE" forum. It's ok to hate Obama, but somehow it is entirely irrelevant to this entire forum. Focus: Merck.

Huh?..do not meet your demographics, at all.

Look in the mirror for signs of anger.

Get over yourself.
 




Yes Alan Sachs was an idiot as was Peter, but once Merck scientists were put on siRNA major advances were made . Several candidates ready to go in the short term, lots of potential for more. A huge opportunity in novel space that Roger always talks about is right under his nose and it's going to be squandered. A chance for Merck to lead in a new area and we will piss it away. It's not just a platform technology anymore , don't believe all the propaganda that you hear. The end of siRNA is politically beneficial for some key leaders in MRL so they have jumped on the bandwagon.

Amgen "hated" siRNA technology. Therefore, siRNA was DOA as soon as Roger arrived. Agree that a lot of progress made once Merck scientists put on it. Keeping a small presence in it would be a strategic play. Any chance something / some people in siRNA will survive?
What a waste.
 




You couldn't be more wrong. - entire MRL effort focused in delivery, and what has been developed is years ahead of anyone else in the field .

Typical Merck denial. We are years ahead. We are the best.

30+ FDA clinical trials with "siRNA" or "RNAi" but not one with Merck as the sponsor. Years of target ID and a focused effort on advanced delivery but we are unable to put them together. Even hepatocytes (easiest tissue to target) and PCSK9 inhibition (anticipated LDL-C lowering blockbuster) couldn't make its way to the clinic? It would appear we are years behind.
 




Merck will be OK. They will outsource all of production, remove all R&D and buy a pipeline. We will then continue to purchase pipelines after that. We will all be happy. Maybe by mid 2017.
 
















Removed from the Dow 30

Honestly, I cannot even fathom how MRK is still in the Dow 30! Bigger fish have been cut loose from the Dow, for lesser reasons: B of A, Citibank, Hewlett-Packard.
MRK needs to be dropped like a block of rotting, compacted sewage. They fail to meet any of the criteria. No longer the standard-bearer. No longer the trend-setter. And shrinking by the day.
 




Amgen "hated" siRNA technology. Therefore, siRNA was DOA as soon as Roger arrived. Agree that a lot of progress made once Merck scientists put on it. Keeping a small presence in it would be a strategic play. Any chance something / some people in siRNA will survive?
What a waste.

Nothing will survive - we will sell it to someone . Then once another company gets a drug, we will buy back in, like we always do
 












1. another major workforce reduction dominating news
2. outsource of most the sales jobs
3. contractors account for 30% of the work force
4. rumor about a merger with Wuxi and change of name into Wuxi Merck
5. named one of the worst companies to work for
6. increase of executives' pay by 50% and decrease of employees' pay and benefits by 20%
7. only 10% of current viewing on Merck board because of massive sales job cut
8. cafepharma messages more positive because only managers are left and come here to troll
9. except for Roger P and Peter Kim posting anonymous messages on Cafepharma, blaming each other for ruining such a great company
10. you and I will be so bored because of fewer postings to read if I still care
 




Start of 2016:

1) Major accounting discrepancies hit the media. It starts as a small whistleblower investigation, and eventually makes its' way to CNBC and Wall Street Journal. Merck will be caught red-handed cooking the books, Enron style. Investors were lied to for several straight quarters.

2) Last few half-functional remnants of MRL R&D sold off in their entirety to Chinese outfits, as Merck corporate struggles desperately to prop up their short-term cash reserves. The 1 or 2 "gems" left in the MRL pipeline are then tested on Chinese death-row prisoners. Candidate compounds prematurely execute 20% of the prisoners dosed.

3) Frasier, Perlmutter, and Kellogg all retire within a 2 month period.

4) Accounting scandal continues to grow. Merck files for Chapter 11, while simultaneously announcing a 40% layoff of the already skeletal workforce.

5) Peter Kim resurfaces to write an editorial in the New York Times. He blasts the "interpretation" of the Chinese death-row study (#3 above). "In reality, only 18% of the prisoners died due to the sold-off MRL compounds", he writes. "When taken as directed, these compounds are an important therapeutic regimen in the management of chronic pain. The stupor and subsequent coma they induce is highly effective at mitigating the pain signals these patients experienced previously".

6) End of 2016: Following Foxconn's example, Merck erects catch-nets above sidewalks of its' remaining buildings, to mitigate the 5-fold increase in employees jumping to their deaths. Foxconn sues Merck for catch-net patent infringement. Ken Frasier comes out of recent retirement to head up Merck's catch-net defense.

7) Merck sends Holiday greetings to its remaining employees. Everyone gets a "Be Well" coffee mug and a year's supply of Kool-Aid. Happy 2017!

This is so funny. You are smart. You should be running the company or a tv show like the daily show.
 








More relevant: What will Merck look like on Jan 1st, 2014?

Ok, so like you remember that scene in Goodfellas, where Joe Pesci opens up the trunk and he's got a guy bound up with tape and ropes in the trunk? And then Pesci starts plunging a knife deep into the poor guy's abdomen. Then the camera angle shifts so you do not see the knife entering, but you hear about 10 nasty "squishy" sounds as Pesci keeps plunging the knife through the guy's intestines. Anyway, 2016 is when the "squishy" sounds are finally completed. In Jan 2014 we'll be at about 3 squishy sounds. Still alive, but not for long.
 








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