anonymous
Guest
anonymous
Guest
OK - there's a lot of opinions here. As a current employee in the cardio unit, I'll share my thoughts:
- Continuity - REGN is unique from many biotechs in that its core leadership (CEO and CMO) has not changed in 30 years. Len Schleifer and George Yancopulous (sp) started the company in 1988.
- Culture - oooh, REGN is, on paper, a small biotech company. On the Eylea or Dupixent teams, you've experienced more of that. Here, working across the Alliance with Sanofi where 1) we don't have leverage 2) nothing matters, since we don't make money 3) until recently, SNFI reps outnumbered us, and 4) SNFI reps mostly have no biotech experience - we feel like a Big Pharma company.
- Praluent: Works better than advertised, and we should have outcomes for not just morbidity, but mortality that separates us from Repatha in next 12 months. It's one of the best drugs you can sell, and our "splash zone" is huge - e.g. patients who've had a cardiac event and re: statin - can't tolerate, or it's not enough. That's like 8-12MM patients in the U.S.
- Amgen has competed well against upstarts like REGN. They do things that are very different than us, probably illegal, and yet effective. It's not clear if we can beat AMGN, who will fight "dirty". Our approach is the high road (better research, not hiking prices, etc.).
- At REGN: R&D > Commercial. The good news: the R&D is impressive - proprietary fully human MAb technology end-to-end... if you have a disease with 1-2 well-characterized protein targets, we can probably build a biologic to beat it. The rock stars at REGN wear white lab coats, and that floats the stock price. Bad News: in the Commercial world - Field has no leverage against say, asinine expense reporting requirements, or HR (you get 18 days PTO, but NO sick days!).
- You have to make your decision on your priorities. REGN is a great place to make a career. But if you want to make a pile of $$$ quickly, and move on - the entire organization does not look at the world like that. For example - the REGN oncology franchise was so promising that SNFI committed to $2B up front. So this is a place to be for the long term.