IMPROVE-IT

[Anonymous]

The trial was initiated in 2005. Will this dog ever be completed? If so, will the results ever be published? If so, will the results show that ezetimibe was all smoke and mirrors?

 

[Anonymous]

Sometime after Zetia is generically available, the "surprising" results of Zetia's utter worthlessness will be announced.

Next, the law suits will commence from every state in the union. It will cost Merck billions in compensatory damages, but not nearly as much as Merck bilked the entire population out of along the way.

25 years ago, we would have not misled anyone. We would have manned up, admitted the trial was an abject failure and taken the hit. This is NOT the Merck of 25 years ago. And we wonder why no one trusts this company, myself included.

 

[Anonymous]

The trial was initiated in 2005. Will this dog ever be completed? If so, will the results ever be published? If so, will the results show that ezetimibe was all smoke and mirrors?

Zetia isn't even smoke and mirrors. It has never done much of anything and benefits absolutely no one except Merck.

 

[Anonymous]

The trial was initiated in 2005. Will this dog ever be completed? If so, will the results ever be published? If so, will the results show that ezetimibe was all smoke and mirrors?

The trial release date was expected in 2011(?) and that is when 18,000 patients were "added". You don't add patients unless your results SUCK! No outcomes data 10 years after launch, yet the drug brings in millions or billions of dollars for Merck. Unbelievable!!! The patent expires 2017, my guess is that IMPORVE IT releases the data in 2016 and the lawsuits start that day.

 

[Anonymous]

The name of the trial is interesting. The marketing team felt they needed to Improve their message, so they came up with a never ending outcomes trial to Improve It

 

[Anonymous]

What IMPROVE-IT has already proved is that doctors will prescribe about anything regardless of whether there is any proof that it helps their patient. And it also proves that regulatory bodies will accept any amount of stalling while the companies they regulate harvest lots and lots of money. If it turns out that Vytorin is not any more effective than Zocor - as many suspect - the strategy of delaying the proof will have paid off handsomely for Merck and the public will have been duped once again by Merck.

 

[Anonymous]

What IMPROVE-IT has already proved is that doctors will prescribe about anything regardless of whether there is any proof that it helps their patient. And it also proves that regulatory bodies will accept any amount of stalling while the companies they regulate harvest lots and lots of money. If it turns out that Vytorin is not any more effective than Zocor - as many suspect - the strategy of delaying the proof will have paid off handsomely for Merck and the public will have been duped once again by Merck.

Merck is managing IMPROVE-IT to the letter of the law, but don't think for a minute that those at the FDA don't know what's actually going on. Merck will have to pay a price for this when some whistle blower steps forward with an email. When you're sh!tting on your employees, this sort of thing happens often. Merck deserves what it has coming.