IMPROVE-IT November official.

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Anonymous said:
Correct me if I am wrong here, but wouldn't they have halted the study if there was an apparent risk of death, or increased harm with Zetia vs. other arms? Furthermore, wouldn't the study have been stopped early if there was clearly a very significant reduction in events/mortality rates in the Zetia arm? Therefore, it seems to reason there is going to be either no benefit or slight benefit in outcomes data. All of which could be partly related to the study design.
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You are correct Sir (RIP, Ed) !
 




You do not know what the outcome will be. Signs point to this being alright. Outcomes are not going to be huge, but should be decent. We will survive and continue to breathe after the results are announced. Too many drama lovers!
 




IMPROVE-IT negative or even neutral will be the end of the lipid franchise. DOJ's from every state will file class action to recoup monies paid over the years by states for a worthless product.

Settlement could be 10+ billion.
 




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