how do you say.....

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The amazing thing is the way they are doing free test for the people that have insurances that will not pay! and the can't collect.

The EOB's come to the patients saying the patient does not have to pay for this service since they are out of network.

How much longer can they do pathology and not get paid?

Lets say most of them are not going to pay them effective this summer
 






Foundation has money and will do the test free. attempted to get a case the other day and the doc said, he preferred foundation for that reason. the differences though many were not sufficient to overcome the fact of the dollar difference. this is a big issue.
 






United Healthcare, Cigna and Aetna will be the next ones to drop the axe on this company! They will being going after them big time, look out the end is near once the offices get the heads up from these plans. No offices will be able to send to them in fear of getting hit hard by the insurance companies.

keep writing off the plans that are not paying = free path + the 50%cuts on the 88305 TC part while the offices based labs are doing the PC, how much longer will this go on?
 






Anonymous said:
Foundation has money and will do the test free. attempted to get a case the other day and the doc said, he preferred foundation for that reason. the differences though many were not sufficient to overcome the fact of the dollar difference. this is a big issue.
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I will tell you though (I do not work for either company, I am a VC follower and troll to see what i can find out from the real people-the reps,)The reason Foundation has caught on is because they have several big name employees and principles that are using their "connections". They know where the grant money is and when not available they eat the cost. None of these in my opinion are safe bets right now. Eventually this will all work itself out and all these companies are going to be required to have FDA approval and all waivers. I feel as if these products will have to be commercialized and sold through vendors like Ventana, Leica, DAKO, etc... Etc...
 






like a companion diagnostic? You could be right. I think the main concern is the cost to the patient because depending on where they are in their deductible a MP test could be very costly. Impending bundled payment will not allow for dollars spent on these types of tests. Insurers, and hospitals will be determining how those dollars are utilized and the players include anyone or thing that touches the patient i.e. the doctor, specialist, facility, all tests and services, ancillary providers, and I could go on. Established guidelines and care protocols will determine how dollars are spent. The insurers will be looking to reduce big ticket items (especially when efficacy is not guaranteed)in favor of approved spend (even though treatments are often a waste of dollars). All companies, Caris, Foundation, Genoptix etc.. will need to prove that money is saved by MP. That is a tall order but one that is really a requirement with our "brand new health care system" I do not agree with much of the ACA but it is here and we have to do things differently to stay in the game.
 






What are you some kind of ACA supporter? You sound knowledgeable but the real issue is the leadership of these companies is all for the leaders and not for the patients or providers. Take Caris for example. That place is full of leadership that has rarely been in the field and is completely ignorant of the fact that pricing must be modified to meet the demands of the what is going in in health care. Most of the leaders especially LB, TS, JM, and of course the fathead DH are only worried about themselves and not what is going on out here as we struggle to make sales. We are giving them a quick profitable hit that has no longevity for the long term. But that is what DH wants as he is looking for money to support his real love carisomes. By the way, anyone who thinks he is dumping money in this company out of the goodness of his heart, knows shit about business. He sees value in carisomes and nothing else and will dump the MP portion as soon as he makes it look real good.
 












circulating micovesicles seem a ways away.......could be useful someday but once you already have the mutated/WT answer and start/do not start therapy why monitor epithelial changes?

Seems like an updated MRD test for patients with short survival.

Do not get me wrong, companies are researching it - or letting others find the breakthrough and then buy their technology/research.
 






Very good points, however the advantage of developing a sensitive blood based test would be earlier non invasive detection prior to symptoms arising in addition to temporal monitoring capability. Most chemo is not effective and therefore being able to redirect treatments would be of huge value to the oncologist. This is not the case with traditional tissue based assays which are conducted only after symptomatic disease is present. Another limitation of tissue testing is its invasive nature or the unavailability of tissue to evaluate when primaries have previously been resected such as for example in breast cancer. Not to confuse exRNA blood testing with susceptibility assays such as for BRAC mutations which are strictly probabilistic with dramatic preemptive treatments. The issue with the EMBRACE1 study in my opinion is the over reliance on known non specific markers. But who knows it might be the one to put CLS on the map.
 






Maybe my first intelligent CP conversation........you know more than I as I am in Product Development and have other new test closer to market as my focus but I do keep an eye out on the potential future.

Still waiting for MicroArray to rule the world........only been 10 years lol.
 






Anonymous said:
Gail Marcus was paid $50/share when she left. The rest of us got $5.07/share. At the time of the sale the company was even bigger than when Gail was there. Read the complaint on the links, and be enlightened. The Texas Billionaire who claimed it was not about money, but rather to releave suffering has been proven a liar. It is about his money and our suffering. A billionaire taking from the workers; theft throught deception and manipulation. How much is enough, DH?
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Based on the judge’s belief from the record as to what TargetNow and Carisome’s true valuations were, the fair market value of a Caris share was adjusted from $5.07 to $6.57, and TargetNow/Carisome went from $0.61 per share to $2.10 per share.

After subtracting proceeds already received, the judge awarded the class $16.3 million plus pre- and post-judgment interest, compounded quarterly since November 22, 2011 until payment.

The judge determined the Caris board violated the conditions of the Stock Incentive Plan by failing to determine fair market value or adjust the options to account for the spinoff.

Interestingly, in order to defend themselves, Martino and Halbert argued they engaged in fraud when they provided the projections upon which the valuation of TargetNow was based for the purposes of its potential sale. Halbert testified the projections were “fantasy land, “an impossibility”, and “intentionally exaggerated”, and Martino stated he did not believe at the time there was any way TargetNow could achieve the numbers in the projections.

This presented an issue for the judge: Martino and Halbert were asking him to believe they were telling the truth during testimony when they claimed to be lying to bidders back in 2011. The judge called this a “double-liar problem”.
 






Anonymous said:
Only way to get ROI from carisomes is to have predictive clinical data. It all depends on the outcome from EMBRACE1 for prostate. The future depends on those results.
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LOL looks like someone figured out how to make a prostate test based on exosomes and it wasn't you. It will never be yours...because it never was a problem money alone and ass kissing could solve. It takes brains, of which you are in very short supply! Hahahahaha!!! Oh yes, you were told by the Wunderkind (who couldn't figure out how to do it) it couldn't work, antibodies are DANGEROUS! You believe whatever the little imp tells you, don't you? This AND Foundation eating your 8 year lead in no time. Oh man, I'm laughing so hard at you fools my stomach hurts... In a really good way.
http://www.exosomedx.com/news-event...ounces-publication-exointelliscoretm-prostate
 






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