Turn Out The Lights, The Party’s Over-
Lupkynis Faces Challenges In Lupus
Nephritis Market
Mar. 21, 2023 5:57 PM ET | Aurinia Pharmaceuticals Inc.
Summary
• Despite positive results from the AURA-LV study, Lupkynis has not become the preferred LN treatment, leading to Aurinia's missed 2022 revenue projection.
A study indirectly comparing drug regimens for LN induction therapy indicates tacrolimus plus MMF is likely the most effective, followed by Lupkynis plus MMF.
Per prominent treatment recommendations, voclosporin, the active ingredient in Lupkynis, is recommended as a viable alternative for initial LN therapy, but not as the top choice.
Although there has been a legal settlement, Aurinia's treatment protocol patent may still be subject to questioning, which could potentially enable competitors to enter the market when the exclusivity period ends in 2026, despite providing some protection against generic competition.
Aurinia's Lupkynis, SELL, SELL SELL