Viridian aims to prove itself in thyroid eye

Horizon Therapeutics’ Tepezza is the only drug approved for thyroid eye disease, and last week its reach increased. In the wake of data suggesting Tepezza works in patients with chronic but mild disease, the FDA approved a change to the drug’s label, specifically stating that it can be used “regardless of thyroid eye disease activity or duration”.

Whether payers will expand reimbursement to match is another question, though with Amgen's takeover of Horizon in the works powerful marketing muscle could soon be brought to bear. What is not in question, however, is that a competitor is hard on Horizon’s heels. Viridian Therapeutics will shortly report mid-stage data on VRDN-001 in both chronic TED, and success could begin to change the landscape.