Scientists at Penn’s Perelman School of Medicine screened existing drugs in several cell types, including those that line human airways, to see whether they could inhibit SARS-CoV-2, the virus that causes COVID-19. Nine were particularly effective in respiratory cells, three of which are FDA-approved: Pfizer’s lung cancer drug Vizimpro (dacomitinib), the antibiotic salinomycin and cyclosporine, which is used to prevent rejection in patients receiving organ transplants. They published their findings in the journal Cell Reports.
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