Ionis, Rockefeller team find peripheral blood target for Alzheimer's

Ionis Pharmaceutics Inc. (NASDAQ:IONS) and The Rockefeller University found blood plasmin drives Alzheimer's disease progression and immune responses in the brain, shedding light on neuroinflammation's role in AD. The team suggested antisense oligonucleotide depletion of plasmin's precusor, plasminogen, in peripheral blood can protect against AD development.