After AL amyloidosis flop, Prothena slashes workforce by 57%

To say that Prothena had a turbulent year would be an understatement. In the span of a month, the biotech went from inking an R&D deal with Celgene worth up to $2 billion to dumping its lead asset, an AL amyloidosis drug, after it missed its primary and secondary endpoints in a midstage test with a poor prognosis for phase 3.