4DMT provides clinical programme updates for its wet AMD gene therapy

4D Molecular Therapeutics (4DMT) has provided a timeline for the development of 4D-150 to treat wet age-related macular degeneration (wet AMD).

4D-150 is an intravitreal vector-based therapy developed using the therapeutic vector evolution platform as an adeno-associated virus vector to deliver an anti-VEGF transgene that expresses both aflibercept and a VEGF-C inhibitory RNAi, to treat wet AMD.