Xolair is a great drug which has been poorly promoted because of the silly partnership between Genentech and Novartis. The increases in sales are simply due to price increases. That is why I stopped my 3 vials per month as the cost got out of control. My insurance would not cover enough so I went back to inhaled steroids and others which do ok but not as good a Xolair. Caremark never told me about any support for copay so I can't restart now according to BCBS