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What Factors Lead to the Demise

I don't work in LRL but if it's anything like sales and the bogus things we put on our DAPs every year, that could be the problem. It may sound like this. 1. Develop 40 molecules to be put thru phase 1 development. This is to achieve the needs of shareholders and Wall Street, nothing really having to do with new development of innovative molecules. Just something JL can brag about..... We have 250 molecules in phase 1, when everyone knows that nothing will ever come of any of them. What Lilly really needs is TRUE innovation. If we can't do it internally because our lame PM process then we need to change it NOW but in the mean time go outside Lilly and work with a lab that has something innovative in phase 3, that is TRULY innovative and almost a sure thing in getting FDA approval! At the same time lets spin off a subsidiary that manufacturers generics!!!

I am a chemist. I don't work for Lilly and would not work for Lilly.

But I can tell you that you are correct about this statistical mumbo-jumbo hocus-pocus.

You want to see real medicinal chemistry? Look at what they do in France or Russia. There is just no comparison to Lilly. Never. Never in 150 years has Lilly ever come even close. You people are just too conservative. Sorry.
 




I don't work in LRL but if it's anything like sales and the bogus things we put on our DAPs every year, that could be the problem. It may sound like this. 1. Develop 40 molecules to be put thru phase 1 development. This is to achieve the needs of shareholders and Wall Street, nothing really having to do with new development of innovative molecules. Just something JL can brag about..... We have 250 molecules in phase 1, when everyone knows that nothing will ever come of any of them. What Lilly really needs is TRUE innovation. If we can't do it internally because our lame PM process then we need to change it NOW but in the mean time go outside Lilly and work with a lab that has something innovative in phase 3, that is TRULY innovative and almost a sure thing in getting FDA approval! At the same time lets spin off a subsidiary that manufacturers generics!!!

The entire pharmaceutical industry is like this in the US!!!! It's like kicking the can down the road!! Developing bogus molecules in research labs to appease shareholders when in fact we need TRUE innovation in order to survive! This is not the same industry that it was in the 1980's! This is truly a dying industry. GET OUT NOW!!!! Get rid of all top leaders in the company!
 




The entire pharmaceutical industry is like this in the US!!!! It's like kicking the can down the road!! Developing bogus molecules in research labs to appease shareholders when in fact we need TRUE innovation in order to survive! This is not the same industry that it was in the 1980's! This is truly a dying industry. GET OUT NOW!!!! Get rid of all top leaders in the company!

To borrow an analogy, I see Lilly as the Canary in the Coal mine of the pharma industry. I see many similarities between Lilly and Enron. Nonsense I hear some say but if you look at the way that Lilly created its "pipeline" it is not a leap to see the similarities with what Enron did re selling non existent energy futures.

I believe that Wall Street will inevitably turn up the heat, as the window of opportunity for Lilly to bluff its way out of the patent cliff with its pipeline is closing fast. Indeed I'd argue its already shut.

I don't disagree with your contention that the issue of creating metric driven drug development projects that are based on flimsy science to appease Wall street is an industry wide problem, but at many of Lillys peers have got some successes in getting some decent drugs to market. Take Pfizer as an example....may not like them but they are weathering their patent cliff better than most and have consistently brought some new drugs through development to offset some of their losses from the Lipitor patent expiry.

Lilly on the other hand has brought diddly squat of any significance. This will end very badly for Lilly IMO. Don't be surprised if we wake up some morning to find that Lilly is in receivership. Motorolla anyone a.k.a the break up of Lilly, by the vultures in Wall St and a spin off of anything left of worth?
 




To borrow an analogy, I see Lilly as the Canary in the Coal mine of the pharma industry. I see many similarities between Lilly and Enron. Nonsense I hear some say but if you look at the way that Lilly created its "pipeline" it is not a leap to see the similarities with what Enron did re selling non existent energy futures.

I believe that Wall Street will inevitably turn up the heat, as the window of opportunity for Lilly to bluff its way out of the patent cliff with its pipeline is closing fast. Indeed I'd argue its already shut.

I don't disagree with your contention that the issue of creating metric driven drug development projects that are based on flimsy science to appease Wall street is an industry wide problem, but at many of Lillys peers have got some successes in getting some decent drugs to market. Take Pfizer as an example....may not like them but they are weathering their patent cliff better than most and have consistently brought some new drugs through development to offset some of their losses from the Lipitor patent expiry.

Lilly on the other hand has brought diddly squat of any significance. This will end very badly for Lilly IMO. Don't be surprised if we wake up some morning to find that Lilly is in receivership. Motorolla anyone a.k.a the break up of Lilly, by the vultures in Wall St and a spin off of anything left of worth?

Totally agree with this assessment. Elanco animal health unit has some remaining value, so could be spun out of this sinking ship. Also, some of the manufacturing capacity in insulin (a Chinese concern maybe ?) and biologicals (Imclone and Ireland) may be of use to someone that knows how to develop biotech drugs. More likely, they will wait until Lilly goes belly up and pick up these assets at pennies on the dollar with tax breaks from local government for 'saving' some jobs.

Very likely, the patented drug industry has only begun to feel the pain and LLY will be the first of several to implode.
 








Totally agree with this assessment. Elanco animal health unit has some remaining value, so could be spun out of this sinking ship. Also, some of the manufacturing capacity in insulin (a Chinese concern maybe ?) and biologicals (Imclone and Ireland) may be of use to someone that knows how to develop biotech drugs. More likely, they will wait until Lilly goes belly up and pick up these assets at pennies on the dollar with tax breaks from local government for 'saving' some jobs.

Very likely, the patented drug industry has only begun to feel the pain and LLY will be the first of several to implode.

"Animal health" is dying thanks to consumer backlash and the FDA and USDA can only follow.

Insulin? Should not be necessary. Almost all diabetes is Type II and the cure is diet and exercise (which, incidentally, also prevent or even cure Alzheimers and some Parkinsons)

Imclone? Sure, sell it for a nickel on the dollar, it will be less of a drain.

The stock price is still high, with very little apparent shorting. My best guess is some of the hedge funds are already sending their sharks into the dark pools of Wall Street to check out the prey.

Indianapolis, Carmel and Fishers might be the next urban blight areas...

Hey, I am not happy about this either. It's very sad, but the religious right at Lilly pretty much controls the politics locally, and the business is all controlled by the Ken Lays (or wanna-bes or equivalent) of Wall Street and borderline failure MBAs and investment bankers.
 




To come full circle, never forget that KEN LAY was a board member of this "fine place." He locked it into a long-term, multi-billion dollar "energy management" contract with...guess who? Guess who also advocated the "rank-and-yank" PM template? You could see it coming in the fog.
 




To come full circle, never forget that KEN LAY was a board member of this "fine place." He locked it into a long-term, multi-billion dollar "energy management" contract with...guess who? Guess who also advocated the "rank-and-yank" PM template? You could see it coming in the fog.

The blind led by the scum.
 




The blind led by the scum.

I'm afraid upper management is and has been over their head, they're not sure how to get out of this mess. With incompetence it's easy to get here. Lilly tried to get into biologics i.e. Biotech but they never could figure that one out so they try to do it the easy way buying hopeless entities like Imclone. Sorry John but Lilly is dying a slow death.
 




"Animal health" is dying thanks to consumer backlash and the FDA and USDA can only follow.

Insulin? Should not be necessary. Almost all diabetes is Type II and the cure is diet and exercise (which, incidentally, also prevent or even cure Alzheimers and some Parkinsons)

Imclone? Sure, sell it for a nickel on the dollar, it will be less of a drain.

The stock price is still high, with very little apparent shorting. My best guess is some of the hedge funds are already sending their sharks into the dark pools of Wall Street to check out the prey.

Indianapolis, Carmel and Fishers might be the next urban blight areas...

Hey, I am not happy about this either. It's very sad, but the religious right at Lilly pretty much controls the politics locally, and the business is all controlled by the Ken Lays (or wanna-bes or equivalent) of Wall Street and borderline failure MBAs and investment bankers.

Whoa, wait a minute. Lilly is not a religious right company. The company supported The ACA. They're the major funder behind the gay marriage support crew. They support open borders, immigration amnesty. JCL loves BHO. Bart has more influence than Alex, simply because of political affiliations. There is nothing conservative this company supports and they run from everything conservative. You need to get your facts straight, millennial progressive bum!
 




"Animal health" is dying thanks to consumer backlash and the FDA and USDA can only follow.

Insulin? Should not be necessary. Almost all diabetes is Type II and the cure is diet and exercise (which, incidentally, also prevent or even cure Alzheimers and some Parkinsons)

Imclone? Sure, sell it for a nickel on the dollar, it will be less of a drain.

The stock price is still high, with very little apparent shorting. My best guess is some of the hedge funds are already sending their sharks into the dark pools of Wall Street to check out the prey.

Indianapolis, Carmel and Fishers might be the next urban blight areas...

Hey, I am not happy about this either. It's very sad, but the religious right at Lilly pretty much controls the politics locally, and the business is all controlled by the Ken Lays (or wanna-bes or equivalent) of Wall Street and borderline failure MBAs and investment bankers.

This Lazy Liberal Millenial couldn't be more wrong about Lilly political affiliation.
 




To come full circle, never forget that KEN LAY was a board member of this "fine place." He locked it into a long-term, multi-billion dollar "energy management" contract with...guess who? Guess who also advocated the "rank-and-yank" PM template? You could see it coming in the fog.

Ken Lay really had little influence during his short tenure.
 








"Animal health" is dying thanks to consumer backlash and the FDA and USDA can only follow.

Insulin? Should not be necessary. Almost all diabetes is Type II and the cure is diet and exercise (which, incidentally, also prevent or even cure Alzheimers and some Parkinsons)

Imclone? Sure, sell it for a nickel on the dollar, it will be less of a drain.

The stock price is still high, with very little apparent shorting. My best guess is some of the hedge funds are already sending their sharks into the dark pools of Wall Street to check out the prey.

Indianapolis, Carmel and Fishers might be the next urban blight areas...

Hey, I am not happy about this either. It's very sad, but the religious right at Lilly pretty much controls the politics locally, and the business is all controlled by the Ken Lays (or wanna-bes or equivalent) of Wall Street and borderline failure MBAs and investment bankers.

You need to learn a few things about medicine. Animal Health is big business and does not have any 'consumer backlash'. Type 1 diabetes is growing fast. Type 2 can sometimes be improved with diet and excersize. Alzheimer's and Parkinson's cannot.

Get a clue about the facts.