Trifexis is working very well so far in many of my accounts. The dermatologist speaks the real truth, and after seeing the newly revised AE list for crapstr, I'm glad to see it go to the waste basket. Everyone is switching to sexy Trisexis. My bet is all in for Elanco.
Trifexis
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Seems to me that sentnl is shrinking like a small weenie in cold water. Should have added cialis! Sorry boys. Polish that resume. I heard the real blockbuster is hiring and growing . . . again.
We recently got a 2 year old Anatolian Shepard. It was shipped through 2 states by car and given Trifexis the morning it started the journey. She vomited 1 hour after taking it. approximately 24 hours after taking it the dog had what appeared to be an epileptic seizure. It was in a room alone with no noise or stimuli that may trigger a seizure. The prior owners say they have never witness this ever before with this dog. The dog is also in estrus.
Would Trifexis be a contributor to this seizure?
Would Trifexis be a contributor to this seizure?
The novartis rep who posted this fiction should grow a brain. Nobody who reads this crap would believe that a client would ever think to ask about an AE on this site, and they certainly wouldn't ask the idiots from nvrts. Common sense . . . what a moron. Haha.
Trifexis has a caution label, not a warning, for dogs with pre-existing seizures. Read the label.
Just in case you don't know where to look... Check under PRECAUTIONS. Also, if this was a 'legit' pet owner, I recommend discussing this with a vet, not cafepharma on the Novartis Page. Novartis reps do not like Trifexis, as Trifexis is taking market share ($) from them.
I have a question for any novartis employee who has an honest answer (I know that will be difficult).
I would like to know why the marketing department thought it would be valid, appropriate, and respectable to create a sell sheet which includes charts from two different studies that you didn't complete yourself?
Surely you guys would have first read all pertinent information from each study and realize that the study designs were/are flawed! Neither study holds water in the eyes of educated DVMs, so what made you guys feel that the results would look any better on your brochure?
Try this ... Complete a peer reviewed, double blinded study with 600 fleas on each dog with several different groups of dogs, for a period of 90 days. Examine each dog for fleas every 5 days. Inspect every dog for signs of FAD, alopecia, pruritus, pyoderma, and make some more charts for your brochures.
Could you actually show a better result than Comfortis? My bet as a clinician is NO! Your products don't kill fleas, which allows fleas to eat blood meals all day, every day . . . and all night too. Yuk!
Congratulations to Elanco for getting it right. Trifexis is now the leading product in our clinic, we switched from Comfortis.
I would like to know why the marketing department thought it would be valid, appropriate, and respectable to create a sell sheet which includes charts from two different studies that you didn't complete yourself?
Surely you guys would have first read all pertinent information from each study and realize that the study designs were/are flawed! Neither study holds water in the eyes of educated DVMs, so what made you guys feel that the results would look any better on your brochure?
Try this ... Complete a peer reviewed, double blinded study with 600 fleas on each dog with several different groups of dogs, for a period of 90 days. Examine each dog for fleas every 5 days. Inspect every dog for signs of FAD, alopecia, pruritus, pyoderma, and make some more charts for your brochures.
Could you actually show a better result than Comfortis? My bet as a clinician is NO! Your products don't kill fleas, which allows fleas to eat blood meals all day, every day . . . and all night too. Yuk!
Congratulations to Elanco for getting it right. Trifexis is now the leading product in our clinic, we switched from Comfortis.
Trifexis is a great product and killing Sentinel.
Not a good time to join Novartis. Beaten by competition, nothing in the pipeline and bad management.
Not a good time to join Novartis. Beaten by competition, nothing in the pipeline and bad management.
Hey stud muffin, sorry to hear about your shortness. Nothing seems to be stopping Trifexis, not even your little rooster. Heeheehee . . .
Can't catch a diverter until they actually divert. At least Elanco is trying to do something about Internet sales and keep business in clinic. Online sites not really cheaper than clinics, if even at all, for Trifexis.
What is Novartis, Bayer or merial doing about Internet sales? Prices on those products are CHEAP online. How are clinics suppose to compete w/that?
And as for otc, if you're a vet, Would you rather be 'stabbed In the front' (Bayer) or stabbed in the back (Merial) by your business 'partner'? Or have someone trying to help your business (elanco)?
OR a company that bad mouths other companies with dear doctor letters. wow. that's real classy. not just once, but twice. i'd want honesty, thank you very much. not lies.
Trifexis has no real market share. If they ever get any, we'll see how good their track and trace really is. As long as you know.....doc....you're going against recommendations from thought leaders.....adulticide + IGR.....Trifexis is just an adultcide....and spinosad has been banned in agriculture in several states due to resistence. Google it.
Gave my perfectly healthy 7 year old lab/pyrenese mix trifexis. She had a horrrible, horrible seizure. Animal hospital tested her for everything else at a cost of $5,360. Trifexis is poison.
Period.
We recently tried Trifexis on our dogs. We gave it to two schnauzers and two mix breeds. The next day both of the schnauzers were extremely ill. One of the schnauzers died that day and the other is recovering. The vet has performed an autopsy and sent tissue samples to be tested. The autopsy showed that she was physically in perfect health. The manufacturer of Trifexis is paying for the autopsy and tissue tests. I just wanted to let people with schnauzers know that they should be extremely careful. It had no ecfecton the the two mix-breeds
I can't believe that there are humans that stoop to the level of this filth. The
language this rep uses should be kept to himself. If he can't communicate
with people in a respectful way he should not represent anything of anyone's
product. What a chicken to get on the internet and display his filth for even
children to read. Disgraceful!!!!!
language this rep uses should be kept to himself. If he can't communicate
with people in a respectful way he should not represent anything of anyone's
product. What a chicken to get on the internet and display his filth for even
children to read. Disgraceful!!!!!
I just gave my 8.5 month old Borzoi his second dose of Trifexis. Within 20 minutes of giving him the pill he threw it up along with a small amount of food. He did this when he took the first dose a month ago too. I let him eat his throw up the first time immediately after he threw up, as I did not want to re-dose him, not knowing how much could have been absorbed verses how much may not have been absorbed. One would logically assume since this is a combination drug, the chances for adverse reactions could increase as the dose increases(especially in an animal that vomitted it up two times). Given this drug apparently stays active for up to a month, I would not want to increase the dosage of something that could have potentially adverse reactions, as I would have no way of clearing the meds from his system in a time efficient manner should he show other adverse reactions.
Today, as I said upon giving the second dose he did throw up, but he would not eat all of what he threw up. So, I have no clue how much drug got absorbed, but I will not re-dose him, and will wait to see if he stays clear of fleas. He has not had a flea problem since he took the first dose, so it has been extremely effective against fleas.
The concerns I have with Trifexis are this: After he took the drug, his skin would have a distinct smell, and he blew most of his coat, and his hair looks dull. His coat prior to taking this medicine was coming in healthy, shiny and full. He is kept inside with the AC and only goes outside for brief bouts of exercise and to relieve himself. Yes, it is summer and maybe even though the dog is kept indoors, may go through a seasonal shedding, it just seems the shedding of the coat along with the dullness are directly related to his intake of the Trifexis. The other concern is, if the dog keeps throwing up his dosage, the cost would definitely be prohibitive. The first time like I said he immediately ate his throw up, (I know this sounds gross, but given the cost of the meds, I felt it was okay), but today he did not eat it all immediately and thus after about 2 hours I felt I had no choice but to remove it from him in case he would choose to eat it later. He ate most of it, and hopefully he got most of the medicine.
Consider the following:
1)For me to spend $104.00 on a 6 month supply and have him throw it up two times on two different occasions is problematic concerning his health, and the safety of the meds!
2)For me to EVEN have to consider allowing my dog to eat his throw up to get the medicine in him for absorption is utterly ridiculous, even though cost effective!!!
3)Had I not allowed him to eat his vomit, that would have meant I would have spent $104.00 divided by 6, multiplied by 4, as I would have had to re-dose him twice to treat my dog for two months totalling $69.33 which is not cost effective!!!
4) I have lingering concerns about how this medicine is effecting his skin and coat, and given he is a pure bred dog whom I would like to have a nice coat, I wonder if mefeeding him a great diet for his overall health, including his coat, is being negated by this medicine. (My thoughts are I will see if his coat looks better in the winter, but I am somewhat disappointed as I feel the meds have destroyed his healthy coat he once ALREADY had grown in)
Well there you have my experience, and concerns. I found this site today as I was doing a search on negative effects of Trifexis, as I was concerned if anyone else had problems with their dogs coats while on this drug.
Today, as I said upon giving the second dose he did throw up, but he would not eat all of what he threw up. So, I have no clue how much drug got absorbed, but I will not re-dose him, and will wait to see if he stays clear of fleas. He has not had a flea problem since he took the first dose, so it has been extremely effective against fleas.
The concerns I have with Trifexis are this: After he took the drug, his skin would have a distinct smell, and he blew most of his coat, and his hair looks dull. His coat prior to taking this medicine was coming in healthy, shiny and full. He is kept inside with the AC and only goes outside for brief bouts of exercise and to relieve himself. Yes, it is summer and maybe even though the dog is kept indoors, may go through a seasonal shedding, it just seems the shedding of the coat along with the dullness are directly related to his intake of the Trifexis. The other concern is, if the dog keeps throwing up his dosage, the cost would definitely be prohibitive. The first time like I said he immediately ate his throw up, (I know this sounds gross, but given the cost of the meds, I felt it was okay), but today he did not eat it all immediately and thus after about 2 hours I felt I had no choice but to remove it from him in case he would choose to eat it later. He ate most of it, and hopefully he got most of the medicine.
Consider the following:
1)For me to spend $104.00 on a 6 month supply and have him throw it up two times on two different occasions is problematic concerning his health, and the safety of the meds!
2)For me to EVEN have to consider allowing my dog to eat his throw up to get the medicine in him for absorption is utterly ridiculous, even though cost effective!!!
3)Had I not allowed him to eat his vomit, that would have meant I would have spent $104.00 divided by 6, multiplied by 4, as I would have had to re-dose him twice to treat my dog for two months totalling $69.33 which is not cost effective!!!
4) I have lingering concerns about how this medicine is effecting his skin and coat, and given he is a pure bred dog whom I would like to have a nice coat, I wonder if mefeeding him a great diet for his overall health, including his coat, is being negated by this medicine. (My thoughts are I will see if his coat looks better in the winter, but I am somewhat disappointed as I feel the meds have destroyed his healthy coat he once ALREADY had grown in)
Well there you have my experience, and concerns. I found this site today as I was doing a search on negative effects of Trifexis, as I was concerned if anyone else had problems with their dogs coats while on this drug.
I had the same experience! My vet put my dog on Frontline Plus and Heartgard Plus. Frontline kills fleas and ticks and no vomiting. The Heartgard is very tasty and covers more parasites than Trifexis.
I hope I can keep him on the Trifexis because it is also suppose to keep whip, hook and round worms at bay. When we got our borzoi a few months ago, he did have whip worm oocysts in his stool. Given, we did not catch it until the 2nd week we had him, the eggs could be in our yard, and/or came from our yard. We burned alot of the yard, and replanted grass, but given I have a shady and moist backyard environment, and live in the South I have to be mindful to take preventative measures against him getting reinfected. Trifexis seems like it would be a triple threat on the above listed parasites. Before we gave him Trifexis, he was given panacur, and durvet triple wormer, and to really eliminate worms animals have to practically be dosed every two weeks for 6-8 weeks and then monthly and then biannually. Thus, if the Trifexis CAN do what it says, and my dog can be healthy and LOOK healthy(nice coat), I really would like to stay with the Trifexis. This afternoon, he seems to be fine, and only time will tell if his coat will get fuller again. I do admit, it is a bit ominous giving my pet a drug combination that is relatively new, as it makes me feel like I'm allowing him to be a test subject