Time to merge!

I agree that practicing physicians understand what drugs do to people, but unfortunately very few of them understand as much about creating new drugs as they believe they do. In reality it can't be a case of either/or, but needs to have both the basic science (biology, pharmacology, medicinal chemistry) and the clinical/medical input to make it work. Having both is unfortunately rare, but always necessary.

To be completely honest, I have lived across a few cultural groups in my short time, and can tell you, there are plenty of really nice natural products that have a marvelous spark for the price of a few cents worth of their tea. Better than Cymbalta by far.

This is something the Colonel would have just loved, maybe even used himself.

Why does a company full of overpaid professionals continuous overlook the obvious?

That to me is the real question.
 






It is so funny to say that doctors/physicians know about drugs. 70% of the doctors only know what the pharma rep tells them to "what is the story". It is the pharmacist who has responsibilityto assess the contradications. Of remaining 30%, nearly half of them are genuinely intelligent and knpow in-depth pharmacological meaning.

At Lilly and may at other places, the "invetor" or "discoverer" cannot be more expert than a docotor, even though the guy or gal had studied in detail PK/PD of the drug up until Phase-II.

Scientists who work on a given drug they "invented" are the supreme knower of the drug effects. However, the drug that becomes marketed, they are deemed totally, 110%
 






It is so funny to say that doctors/physicians know about drugs. 70% of the doctors only know what the pharma rep tells them to "what is the story". It is the pharmacist who has responsibilityto assess the contradications. Of remaining 30%, nearly half of them are genuinely intelligent and knpow in-depth pharmacological meaning.

At Lilly and may at other places, the "invetor" or "discoverer" cannot be more expert than a docotor, even though the guy or gal had studied in detail PK/PD of the drug up until Phase-II.

Scientists who work on a given drug they "invented" are the supreme knower of the drug effects. However, the drug that becomes marketed, they are deemed totally, 110%

Well historically the very best drugs, at least as far as neuroscience is concerned, were thoroughly investigated by the drug discoverers themselves, often through ingestion.

For fun some time, find an old (20 years or more) Merck Index and read leisurely. Oh yeah, they sampled the wares, that's for sure!