the suvorexant story

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Anonymous said:
Where did you see that suvorexant will be bundled with Saphris to Forrest?
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Hey dummy, this drug will NEVER be promoted at Merck. Too many generics and the FDA has already denied the two higher doses. The remaining two doses are garbage. The question is who will pick up the leftovers and buy it from us? We are in a world of hurt and giving this potential product to Mrk pcp sales will never happen. Just maybe, if approved would annual sales peak at 150 million. Shit, we make more with our Crappertone otc suntan lotion. This certainly isn't one of our four pillars, more like a screw on the ground laying near one of those pillars. Copromote? No way in hell. Should be soon when we sell it then we are done with neuro entirely. We could resurface years from now with Alzs but it is way too early to tell. Look at all the neuro products we dropped in phase 3, I count 4 over the past few years. A real shit show. I do think our exec team participated in our Suvo trials as they have been asleep for the past few years. I'm outa here at MRL, we couldn't get a paper clip approved. We would probably uncover a unique AE. Loserexant.
 








The fact that they were developing something in this class with generic Ambien when Ambien is AWESOME - one of my favorites - that offered no advantage, eg, no development of a tolerance, no risk for dependence, no chance to improve sleep quality for those with sleep disorders such as narcolepsy, was a really dumb risk. Looks like this was a pretty bad gamble.
 




Anonymous said:
The fact that they were developing something in this class with generic Ambien when Ambien is AWESOME - one of my favorites - that offered no advantage, eg, no development of a tolerance, no risk for dependence, no chance to improve sleep quality for those with sleep disorders such as narcolepsy, was a really dumb risk. Looks like this was a pretty bad gamble.
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It would have been a loser even if it had made it to market.
 








Merck might be able to sell off the drug to a smaller company. It will be a tough sell however because FDA only wants to approve lower doses and at those doses, it probably doesn't compare very well with Ambien.
 




Anonymous said:
Merck might be able to sell off the drug to a smaller company. It will be a tough sell however because FDA only wants to approve lower doses and at those doses, it probably doesn't compare very well with Ambien.
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I sure is heck wouldn't take a med director position here. Quick hired n fired. Too risky with absolutely zero neuro revenue generated products. This thing is a goner really soon.
 
















Anonymous said:
You might be surprised. There have been a lot of drugs where projected sales were waaay off from what actually happened whether for better or worse. I read that Lipitor was projected to only make ~600 million a year.
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Ahaaaaaaahaaaaaaaaaahaaaa...all the sleep generics and you mention Lipitor. Ahaaaaahaaaaaaahhhhhhaaaaaaaaaa. That's no comparison. Only peeps left with Merck insomnia are the washed up old timers, island of misfit toys. Those hanging on the vine HOPING to stay employed a few more months. DOA, selling it, crappy drug, many generics, incompetent marketing/sales force. Ahaaaaahaaaaaa. Neuro is done at ye ole Merck, the lights have been turned off.
 








Anonymous said:
The major issue is that Merck doesn't have Phase III data comparing suvorexant to Ambien. Withoout head to head data, where is the evidence that the drug is superior?
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Did they ever hire the directors of med affairs for insomnia? Who are these fucks and when do they start? Do they habla ingles? Who is headin up the shit fo brains marketing team for this drugg? Is primary kare sales getting this someday? Come on now, spill the beans.
 




Anonymous said:
Ahaaaaaaahaaaaaaaaaahaaaa...all the sleep generics and you mention Lipitor. Ahaaaaahaaaaaaahhhhhhaaaaaaaaaa. That's no comparison. Only peeps left with Merck insomnia are the washed up old timers, island of misfit toys. Those hanging on the vine HOPING to stay employed a few more months. DOA, selling it, crappy drug, many generics, incompetent marketing/sales force. Ahaaaaahaaaaaa. Neuro is done at ye ole Merck, the lights have been turned off.
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Sleep on.... Nice molecule. Still talent in Neuro. Washed up? Not anymore few to do work. Still some washed up directors hanging around.
 




My in-laws gave me a copy of this article from the the New Yorker to read over the holidays. Interesting article, but t's so LONG that I had to take a nap in the middle of it. Correct me if I'm wrong, but I don't think "sleep" is one of the new categories of focus for our company. Seems plausible that they will sell off this drug to another company.
 




that's the cool thing to do in pharma world now. It used to be Buy every piece of shit that could bring in a buck, not its Sell everything that can't bring in a $1Billion
 




Anonymous said:
My in-laws gave me a copy of this article from the the New Yorker to read over the holidays. Interesting article, but t's so LONG that I had to take a nap in the middle of it. Correct me if I'm wrong, but I don't think "sleep" is one of the new categories of focus for our company. Seems plausible that they will sell off this drug to another company.
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It's a good read whilst using the shitter. I've read it many a time whilst dropping a deuce. Heard some fuckstik madds were hyerd. Was Timiney fyred and what about that turd Rhiodd? That shit fo brains only k ows how to fire, not hire o develop o lead. Now sleep has a few madds with sum phucked up duhgrees. Wtf, couple o phucks talkin off label. What dat gonna do fo us? Sell the sueverxxxent already. Shiiii. T, get my ambien fo pennies a day. Who gonna pay fo a new drugg, who gonna sell it, not murk. U blokes suk. Pull my finger.
 




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