Sell some Zohydro!!

[Anonymous]

Then they do finally write it and the pharmacy won't stock it and the patient has to go out of their normal "day" to go to a stocking pharmacy- which makes them uncomfortable. Then a prior auth kicks in and on and on and on.......

 

[Anonymous]

Then they do finally write it and the pharmacy won't stock it and the patient has to go out of their normal "day" to go to a stocking pharmacy- which make

Which is why Zogenix should discount this product to make if VERY attractive to payers. If they did, you'd be amazed how many of these obstacles go away. Payers only pay attention to one thing: their pay day!

 

[Anonymous]

You are assuming the managed care people know what they are doing and have the approval from Roger & Co. to forego margin for sales. It's September, that should have happened at launch- things are going to get tougher not easier after 6 months with managed care.

 

[Anonymous]

You are assuming the managed care people know what they are doing and have the approval from Roger & Co. to forego margin for sales. It's September, that should have happened at launch- things are going to get tougher not easier after 6 months with managed care.

It's amazing how people can't see the freight training coming for them, but spectators can. They are in deep doo-doo. Having script volume would solve a lot of their problems and keep the lights on long enough to get to ADT

 

[Anonymous]

Boy we sure could have used you around here as you seem to have all the answers. Im glad that you were smart enough to steer clear while the rest of us bought it hook line and sinker. If only...

You are misguided on a few things. First of all with the salary. Many of the reps that were already at Zogenix did not get more money to sell Zohydro because most didn't have pain experience. The new reps that came on did get higher salaries but that was because they DID have experience Certainly you didn't expect Zogenix to let go of the reps that kept this company afloat.

75% of opioids are diverted? I wont disagree with you that opioid abuse is a problem, and needs to be addressed, but where do you get 75%? That's the problem with statistics, 85.98076% of them are made up!

Things are tough right now, there is no denying that. I do believe if we can survive until an ADT form of Zohydro is available the future is bright. If not we'll be out on the streets. Wish we were all smart like you.

Sorry, but have to agree with the poster you responded to. Whatever the number is, almost all (90%+ and these numbers are accurate because hydrocodone is tracked from through distribution) hydrocodone produced is prescribed in the USA, and every stat has abuse and diversion well over 50%. Whether it is 51% or 88% it is way too high and people in this country want an easy fix for EVERYTHING! Ask the average person how they should feel when taking ANY prescription narcotic and they will EXPECT some euphoria! Euphoria? Are you kidding me?! Pain meds should alleviate pain to where you feel no pain, and that's it. It should provide normalcy. If you take it to where you feel "high" or "good" then you are abusing, period!

I don't know about the ones already employed, but I as well know several unemployed reps and reps with no experience who got jobs here for more money that they should have.

 

[Anonymous]

Sorry, but have to agree with the poster you responded to. Whatever the number is, almost all (90%+ and these numbers are accurate because hydrocodone is tracked from through distribution) hydrocodone produced is prescribed in the USA, and every stat has abuse and diversion well over 50%. Whether it is 51% or 88% it is way too high and people in this country want an easy fix for EVERYTHING! Ask the average person how they should feel when taking ANY prescription narcotic and they will EXPECT some euphoria! Euphoria? Are you kidding me?! Pain meds should alleviate pain to where you feel no pain, and that's it. It should provide normalcy. If you take it to where you feel "high" or "good" then you are abusing, period!

I don't know about the ones already employed, but I as well know several unemployed reps and reps with no experience who got jobs here for more money that they should have.

What are you talking about in your comment? I disagree, Opioids simply mask pain, and some euphoria is one of the benefits in this regard. If you take an opioid pain med, then, (some) euphoria will exist until the dosage is no longer effective. However, if an opioid is used correctly, and by this I mean the patient is really suffering from pain, and the patient’s / medical professionals desire is to maximize the opioid’s effectiveness, then, less is more is the correct approach. Increasing the dosage too early can have the opposite to its intended effect rendering it useless.

 

[Anonymous]

What are you talking about in your comment? I disagree, Opioids simply mask pain, and some euphoria is one of the benefits in this regard. If you take an opioid pain med, then, (some) euphoria will exist until the dosage is no longer effective. However, if an opioid is used correctly, and by this I mean the patient is really suffering from pain, and the patient’s / medical professionals desire is to maximize the opioid’s effectiveness, then, less is more is the correct approach. Increasing the dosage too early can have the opposite to its intended effect rendering it useless.

Actually, euphoria is a consequence of a spike in plasma concentration commonly associated with immediate release opioid formulations. With some extended release products, euphoria can be mitigated because the PK profile is altered. I agree with you where patients will feel euphoric sensations if the dose is too high, especially when converting to a different molecule. However starting low and going slow is too conservative of an approach where the physician runs the risk of lack of analgesia which can be a severe consequence in chronic pain patients. The best case scenario is getting the conversion and titration as close as possible to the correct ratio.

 

[Anonymous]

Another person babbling about nothing no one cares about!

This is the place to discuss what is going at Zogenix people!!! Rumors, facts, fiction, venting etc.. If NOT, go somewhere else! Let's get back on track here. Holy hell.

 

[Anonymous]

Actually, euphoria is a consequence of a spike in plasma concentration commonly associated with immediate release opioid formulations. With some extended release products, euphoria can be mitigated because the PK profile is altered. I agree with you where patients will feel euphoric sensations if the dose is too high, especially when converting to a different molecule. However starting low and going slow is too conservative of an approach where the physician runs the risk of lack of analgesia which can be a severe consequence in chronic pain patients. The best case scenario is getting the conversion and titration as close as possible to the correct ratio.

Get the hell out of here with your science and facts!

 

[Anonymous]

Sorry, but you are wrong. Euphoria is a positive for the patient, not for the prescriber. At least not for the prescriber who cares. Euphoria increases, dramatically, the chances of dependency. Starting low and going slow is the appropriate way to go with any drug (lowest efficacious dose for shortest amount of time). It is bad medicine to start at a higher dose than may be needed, as everyone responds differently. Your opinion to be aggressive may help relieve the pain faster but increases the dependency and chance for abuse greatly. This is why these type of drugs are so scrutinized today, cause you act like diversion, abuse and dependency are no big deal as long as the pain goes away as soon as possible.