You might want to re-read the results with glasses & not a microscope. While you are at it, find room with windows.
I have turned my microscope off and opened the shades. Now, you stop drinking the Kool-Aid.
Goodson et al. (paper with OraPharma, Inc. co-author). J Periodontol 78:1568 (2007). Minocycline HCl Microspheres Reduce Red-Complex Bacteria in Periodontal Disease Therapy.
SRP alone reduced bacteria by 5.03%, and SRP + Arestin reduced bacteria by 6.49%. WOW! The difference between those two tiny percentages was statistically significant, but was it really clinically significant? The probing depth and clinical attachment improvements were around 0.35 mm (as opposed to the 0.2 mm reported in the FDA studies), but the SRP alone still did 90% of the work.
Corteli et al. Journal of Oral Sci 50:259 (2008). A double-blind randomized clinical trial of subgingival minocycline for chronic periodontitis.
SRP vs. SRP + Arestin -> "...The results for bacterial frequencies showed no significant differences between groups (Fisher's Exact test, P < 0.05) or between time-points (Friedman test, P < 0.05). We failed to detect any differences between groups related to the presence of target pathogens for 12 months. The effects of both therapies on the microbial flora did not persist for 24 months."
Bonito (meta-analysis). J Periodontol 76:1227 (2005). Impact of Local Adjuncts to Scaling and Root Planing in Periodontal Disease Therapy: A Systematic Review.
"...Differences [in probing depth] between treatment and SRP-only groups in the baseline-to-follow-up period typically favored treatment groups but usually only modestly (e.g., from about 0.1 mm to nearly 0.5 mm) even when the differences were statistically significant. Effects for [clinical attachment level] gains were smaller and statistical significance less common. The marginal improvements in [probing depth] and [clinical attachment level] were a fraction of the improvement from SRP alone. Conclusions: Whether such improvements, even if statistically significant, are clinically meaningful remains a question. A substantial agenda of future research to address this and other issues (e.g., costs, patient-oriented outcomes) is suggested."
Well-played, huh?