Prolia pricing sacrafices PMO for Oncology

[Anonymous]

Ignorant dumb fuck..... what fuckin pharmacy checks you are talking? Reclast AWP is available publicly...redbook, thomson reuters databank etc

just read the comments from one specialist in the article as I am sure you don't have access to any of the shit i mentioned above

http://seekingalpha.com/article/207...ly-to-early-fda-approval-of-osteoporosis-drug

Hey asshole. In my area, they are called HOSPITAL PHARMACIES...ever heard of them? I have longstanding relationships with several metro-based hospitals as I have called on them for years and yes when I called on them selling Reclast. They have shown what they pay for Reclast me as recently as last week when I called on them, and it sure as hell isn't $1100 or less. It's $1400+ infusion fees/charges by the outpatient clinic. If Reclast is $1100 or less in your area, well then that sucks for you, you abviously won't be able to SELL will you. In my Area, Reclast is $1400 and that bolds well for me.

 

[Anonymous]

Hey asshole. In my area, they are called HOSPITAL PHARMACIES...ever heard of them? I have longstanding relationships with several metro-based hospitals as I have called on them for years and yes when I called on them selling Reclast. They have shown what they pay for Reclast me as recently as last week when I called on them, and it sure as hell isn't $1100 or less. It's $1400+ infusion fees/charges by the outpatient clinic. If Reclast is $1100 or less in your area, well then that sucks for you, you abviously won't be able to SELL will you. In my Area, Reclast is $1400 and that bolds well for me.

Butt Wipe...no one is fucking talking about YOUR area and yes I know what hospital pharmacies are... idiot.

A drug price is considered two ways: Average whole sale price (AWP) and average selling price (ASP). Both are calculated through NATIONAL level datasets computations and all relevant projections and analysis are based on that. No one gives a shit about your area as we are talking global revenues here dim wit...

The maximum price points for reclast AWP and ASP this year and last year were 1300. about 75% of the distribution was around 1100....and the rest 950-1000. Hence the average of about 1050.

Fuckin r*****...GET OFF THIS BOARD!!!! you are making me nervous if these are the kind of reps we have in our D-mab sales force. cream of the cream!!!!! Damn

 

[Anonymous]

Butt Wipe...no one is fucking talking about YOUR area and yes I know what hospital pharmacies are... idiot.

A drug price is considered two ways: Average whole sale price (AWP) and average selling price (ASP). Both are calculated through NATIONAL level datasets computations and all relevant projections and analysis are based on that. No one gives a shit about your area as we are talking global revenues here dim wit...

The maximum price points for reclast AWP and ASP this year and last year were 1300. about 75% of the distribution was around 1100....and the rest 950-1000. Hence the average of about 1050.

Fuckin r*****...GET OFF THIS BOARD!!!! you are making me nervous if these are the kind of reps we have in our D-mab sales force. cream of the cream!!!!! Damn

BRAVO!!!!! Finally someone that knows what they are talking about

 

[Anonymous]

Butt Wipe...no one is fucking talking about YOUR area and yes I know what hospital pharmacies are... idiot.

A drug price is considered two ways: Average whole sale price (AWP) and average selling price (ASP). Both are calculated through NATIONAL level datasets computations and all relevant projections and analysis are based on that. No one gives a shit about your area as we are talking global revenues here dim wit...

The maximum price points for reclast AWP and ASP this year and last year were 1300. about 75% of the distribution was around 1100....and the rest 950-1000. Hence the average of about 1050.

Fuckin r*****...GET OFF THIS BOARD!!!! you are making me nervous if these are the kind of reps we have in our D-mab sales force. cream of the cream!!!!! Damn

I don't really give a shit what you claim Reclast is priced in your area or AWP/ASP, all I know is what it is priced in my area and that's all I give a shit about, douchebag! Global revenues, give me a break. I sell in my area and nowhere else. That's all I care about and in my area Reclast is priced on average of $1400. I have seen the fucking price sheets and even have a few copies. So fuck off bitch and go back to your mom's basement.

 

[Anonymous]

I don't really give a shit what you claim Reclast is priced in your area or AWP/ASP, all I know is what it is priced in my area and that's all I give a shit about, douchebag! Global revenues, give me a break. I sell in my area and nowhere else. That's all I care about and in my area Reclast is priced on average of $1400. I have seen the fucking price sheets and even have a few copies. So fuck off bitch and go back to your mom's basement.

In which planet did you sell your Reclast drug?? Planet of the APES!!!

 

[Anonymous]

In which planet did you sell your Reclast drug?? Planet of the APES!!!

Wow, now that's telling him!

 

[Anonymous]

Hey dumbfuck, I f-ing sold reclast and it's not $1150 anymore, especially where I live. They have had two price increases since launch where it was originally priced at around $1150 2 1/2 years ago, dumbass. I have done pharmacy checks and it is priced right at $1400 plus the infusion fees which in my market averages out to be another $75. FU

This is a quote from a comment made by an Osteoporosis Expert (MD) on one of the Forbes articles linked above.

"...BTW, most of my osteoporosis patients only need Reclast every 24 months (which is also how it's labeled for osteoporosis prevention, an indication that was not approved for Prolia).

Also, while the AWP of $1650/year is certainly pretty darn good for a monoclonal antibody, the AWP for Reclast is only about $1048 (or $524 if administered every 2 years, as in most of my patients).

And the efficacy of the two drugs is pretty comparable - here's the fracture efficacy over 3 years in their respective P3 trials:

Morphometric Vertebral Fx: Prolia -68%, Reclast -70%
Painful Vertebral Fx: Prolia -69% , Reclast -77%
Hip Fx: Prolia -40%, Reclast -41%
Non-vertebral Fx: Prolia -20%, Reclast -25%

In other words, while the fracture efficacy with Prolia (denosumab) is quite substantial, it’s not any better then Reclast (and with the exception of morphometric vertebral fractures, no better than generic alendronate).

Otherwise, nice article.

Best regards,

bonedoc"

 

[bonedoc]

Anoymous,

Kudos for avoiding the crude language and profanities so rife on this and all field force chat rooms, and for actually citing your information!

FYI, I stand by the comments I made to the seeking alpha article. I have used Prolia in a couple of patients who were not good candidates for Reclast, but am not currently recommending it for most patients until there are substantially more safety data, especially regarding the magnitude of suppression of bone turnover, which significantly exceeds the effect seen with any bisphosphonate, oral or parenteral.

Regards,

bonedoc

 

[Anonymous]

I don't really give a shit what you claim Reclast is priced in your area or AWP/ASP, all I know is what it is priced in my area and that's all I give a shit about, douchebag! Global revenues, give me a break. I sell in my area and nowhere else. That's all I care about and in my area Reclast is priced on average of $1400. I have seen the fucking price sheets and even have a few copies. So fuck off bitch and go back to your mom's basement.

And Amgen thought they were so smart recruiting "experienced" bone reps with injection experience. LMAO

Novartis is full of ignorant, arrogant a-holes. I'm in Onc there and there isn't a person in the Reclast team that knows shit about reimbursement or buy and bill. I used to beat my head against the wall with these dumasses cleaning up their messes in my offices. Even faced with the most obvious errors they still held fast to their misguided beliefs because corporate had told them and corporate had to be right.

 

[Anonymous]

And Amgen thought they were so smart recruiting "experienced" bone reps with injection experience. LMAO

Novartis is full of ignorant, arrogant a-holes. I'm in Onc there and there isn't a person in the Reclast team that knows shit about reimbursement or buy and bill. I used to beat my head against the wall with these dumasses cleaning up their messes in my offices. Even faced with the most obvious errors they still held fast to their misguided beliefs because corporate had told them and corporate had to be right.

A rep is as good as his sales. PMO reps suck. Simple. Great drug, great price, poor performing reps. We should RIF them all

 

[Anonymous]

A rep is as good as his sales. PMO reps suck. Simple. Great drug, great price, poor performing reps. We should RIF them all

Here here. Stop the blame game trolls!

 

[Anonymous]

Old thread. Came upon it by accident. All the f-bombs in here are kinda funny. Like listening to teenagers argue.

Not sure where the former "Reclast" person's territory is, but here in the US, the AWP for Reclast is currently just under $1300. No Hospital Pharmacy is paying that much for it - they are most likely paying $1100 or less. Yes, I actually buy the drug for a hospital system. Reps are often the last to know the truth - unfortunately.

Pharmer

 

[Anonymous]

This is a quote from a comment made by an Osteoporosis Expert (MD) on one of the Forbes articles linked above.

"...BTW, most of my osteoporosis patients only need Reclast every 24 months (which is also how it's labeled for osteoporosis prevention, an indication that was not approved for Prolia).

Also, while the AWP of $1650/year is certainly pretty darn good for a monoclonal antibody, the AWP for Reclast is only about $1048 (or $524 if administered every 2 years, as in most of my patients).

And the efficacy of the two drugs is pretty comparable - here's the fracture efficacy over 3 years in their respective P3 trials:

Morphometric Vertebral Fx: Prolia -68%, Reclast -70%
Painful Vertebral Fx: Prolia -69% , Reclast -77%
Hip Fx: Prolia -40%, Reclast -41%
Non-vertebral Fx: Prolia -20%, Reclast -25%

In other words, while the fracture efficacy with Prolia (denosumab) is quite substantial, it’s not any better then Reclast (and with the exception of morphometric vertebral fractures, no better than generic alendronate).

Otherwise, nice article.

Best regards,

bonedoc"

Dr bonedoc,

I have a question for you that I want to ask. It may come across sarcastic but it is not. I agree that the fracture efficacy between the 2 products looks similar at 3 years but what do the reclast numbers beyond 3 years show?

The Fosamax trial (FLEX) showed a loss of fracture between 5-10 years. Prolia data to date looks real good. Maybe Amgen knew this when they set the price.