I don't see why you are all being so negative... Remember that Rome wasn't built over-night. With the economy the way it is, this drug will just be a little slower than expected upon climbing to the 2-3 billion dollar a year range. After all, we have much superior efficacy to Plavix and Effient will save many, many lives so it is well worth the premium price... Think about it, what is your life worth to you?