Contrave approved, Looking Damn Good Takeda!!

A 47 page label. Hahahaha. A black box warning of suicide. Hahaha. Increased risks of seizures, BP, HR. hahaha. I guess it is safer. The competitors have none of this. This drug is going to be a joke. Wait until you pull out a 47 page label and Drs see little efficacy and all these risks. Oh, but we have samples of this bad drug. You had samples of Rozerem and edarbi. B and Q are samples also. Read your label. It will only take a month. Hahaha
 




Just heard rumblings that the new safety data from the trials actually show contrave reduces heart attacks and other heart-related issues...

If true this is something no one else in the market would be able to touch...

If true, it is an absolute game changer..
 




I mean, for a second, may I just say why would it not? If it leads to reduction in weight then all co-morbidities will also see a reduction. That is what they were worried was going to be untrue with Contrave initially when data showed a lack of reduction in systolic blood pressure and heart rate when a certain percentage of weight was lost. Losing weight is inherently protective. But if you can take that as your sales point cause its easy for you to ad lib the point home go for it.
 








Untrue. That data is not in the 47 pages of labeling. Warnings about increase in BP. How can that reduce MIs you big dummy

http://www.thestreet.com/story/1287...proved-and-stock-falls-dont-be-surprised.html

Read the last paragraph of the article, unbiased article....

Again, unless you are involved in the upper management or are one of the scientists working on t he drug, not sure if YOU can say they definitely DONT have the data....

I am not saying they do or don't, I am saying there are rumblings that they do and if true, it will catapult this drug to the top
 




Just heard rumblings that the new safety data from the trials actually show contrave reduces heart attacks and other heart-related issues...

If true this is something no one else in the market would be able to touch...

If true, it is an absolute game changer..

So did the Proactive trial for Actos. We all saw how well received that data was and what a great impact it had on sales right? Net ZERO growth.
 




If you want to live 10 years in the past go ahead....

I am here is the present and news flash, rozerem and contrave = not the same class or system...

Keep trolling, we will be busy taking over the market!

Well I guess if we could just dump a single misstep 10 years ago that would make sense. However, Takeda has been rolling in shit with every product launch since Actos. Failed co-promotes with Sucampo, Cephalon and Shire all of which ended badly except for the Sucampo deal because they actually sued us and lost. Failed launch after failed launch. 5 year delay on Nesina. You get the picture.

10 years of nothing but failure sheds a pretty dim light on the potential for Contrave which by the way is also launching about 5 years later than planned.

I think 2 scripts a month per territory is aggressive.
 




OREX stock is down 8.31% and Takeda is down .71% this morning the day after an approval from the FDA. Only Takeda could see their stock price and that of their business partner DROP after an FDA approval. Takeda will fuck this up. Promise.

After a major product approval, OREX stock dropped -10.51% and Takeda finished -.75% down for the day. Arena and Vivus both finished up 1.76% and 1.51% on the news that Takeda is launching (punting) Contrave.

You can't make this shit up.....
 




On the fence, I can see it going either way... But for me, I am leaning more glass half full than empty...

I am not saying this will be a billion dollar drug, but I think it can be solid...
 




Wow, you big dummy. That article says when the CV studies are completed and if the have good outcomes. How can a drug increasing PPR have a positive effect. The most effective drug has less than 1 BPM and sig lowers BP.
 




For those that think the black box is a big deal RELAX. it is no big deal. It is class labeling for all antidepressants. Doctors know this and don't care. What is more worrisome is the fact it is 2 generic products put together. (The FDA just shot down a combo drug of 2 generics). Plus, regardless of what is in a 47 page PI, just the fact that it is 47 pages would cause me not to prescribe. Has any drug, developed for the pcp market, launched with a 47 page PI?
 




It doesnt matter that the PI is 47 pages. What matters is both of these drugs are known to physicians - they know how they work they know about all the warnings. They will give ut to their patients, and it will succeed!! bah bye!
 




Drs hate naltrexone. Why would they give it when it doesn't cause any wt loss by itself. And the SSRIs do not have a black box warning you big dummy. It's just another risk Drs won't want to chance, especially for a whopping 4% placebo adjusted wt loss which is even less than B. C didnt meet any of the FDA criteria for more than 5% more wt loss than placebo. 0 for 4 studies. Explain that to the Drs. Q was 3-3. 2x the efficacy, less SE, less risks and lower BP. Hahaha
 








Just heard rumblings that the new safety data from the trials actually show contrave reduces heart attacks and other heart-related issues...

If true this is something no one else in the market would be able to touch...

If true, it is an absolute game changer..

Cardiologists are only using 1 weight loss drug, why? Neurologists are using only 1 weight loss drug, why? Nephrologists are using only 1 weight loss drug, why? Psychiatrists will only use 1 weight loss drug, why? None of these groups will touch a drug that effects BP or HR.
 




I am trying to work and sell my current bag mix but all my doctors want to talk about is Contrave. They want to know if they can rx now. I cannot wait to sell this drug and it benefits. Gotta go, a PCP is calling me right now.
 




You are right. Once the Drs hear and see the terrible cardio data and see all the risks we will have to beg them to give samples away. What fat person wants a med that will make their PPR increased. Once they see all the patients that can't take this, they will have a heck of a time finding one that is a better choice than the others, especially the one that works 2x better with less SE and risks, oh ya, and lowers BP and PPR. You big dummy.
 




You are right. Once the Drs hear and see the terrible cardio data and see all the risks we will have to beg them to give samples away. What fat person wants a med that will make their PPR increased. Once they see all the patients that can't take this, they will have a heck of a time finding one that is a better choice than the others, especially the one that works 2x better with less SE and risks, oh ya, and lowers BP and PPR. You big dummy.

Not to mention Drs. Are going to pause any time they see a drug promoted by Takeda, given the established record of withholding data, deleting files, etc.

How can a Takeda rep look at anyone and say "our product is safe.....I swear!"