AVASTIN







I never said it was about "making" money on the car. That's your phrase.

I'm just talking about not losing money on a tangible asset. The good news is you can write off those operating cost on your taxes, so if you're in a 25% tax bracket, you'll get some of it back in the form of lower taxes, maybe. Lot's of variables there. Keep good records on business vs. personal miles, because you can only write off for the percentage of expenses that is equivalent to percent of business miles out of total miles and the IRS likes to audit those.

I had the same type of plan with a small biotech years ago. No way you break even on the vehicle when you figure insurance, maintenance, and depreciation.

And yes, I am happy, very happy with where I work and the people I work with. Good luck, and you should certainly hope that GNE does not buy Clovis in the next couple of years.
 












Well, I gave notice this morning. Feels a little weird but, I am relieved at the same time. I think I was a little brain washed to thinking this is the only company to work for, for years. It does have great products but, it is just a good time for me to leave. I will miss some of the people and look forward to seeing good products continue to come from Genentech.
 






Well, I gave notice this morning. Feels a little weird but, I am relieved at the same time. I think I was a little brain washed to thinking this is the only company to work for, for years. It does have great products but, it is just a good time for me to leave. I will miss some of the people and look forward to seeing good products continue to come from Genentech.


Hope the grass is deeper green where you're headed, I found out it wasn't. There isn't a perfect company in this industry, you just need to find the best fit and ride it out, put on your big boy pants, play the game and smile instead of scowl
 






Funny, I did the math and if you are on the legacy GNE car allowance and drive at least 2000 miles per month, you're going to come in about $8K light each year on the Clovis car plan.

They're not giving you anything for maintenance, insurance, and depreciation. You buy or lease the car with the after tax money from the monthly allowance and they pay for your gas. When you need brakes, oil change, transmission service, tires, or other repairs you get to pay for them.

Don't worry though, it will only last a couple of years and then they'll be bought out, perhaps by GNE. Wouldn't that be a bitch?

Congrats, sounds like a solid decision.

You're spot on. Except for the quarter of a million in stock options payout I'd come back to Genentech with if Clovis is bought for the average M&A multiple in biotech the last three years. That $8k really should have factored into my decision, dumbass.
 






Re: Genentech wouldn't buy Clovis comment. Clovis has a lung TKI that essentially works against the mutation (T790M) that causes Tarceva to fail some 70% of time. And Clovis drug is showing that it could work as well as Tarceva, if not better, in patients without that refractory mutation. That's Clovis product 1.

Clovis Product 2 is looking far better than Lymparza for Ovarian/BRCA. Genentech is so uninterested in this second product that we are essentially paying for combo trials with it and PDL-1.

Trust me, Genentech is very interested in Clovis. Freaking BA brings up Clovis as a threat to Tarceva at every QBR. My sense is, the big dogs here are waiting to see how Clovis Product 1 fairs against AZ's new lung TKI, as well as how the combo trial data starts looking for Clovis Product 2.

Listen, why can't these threads be more than just glorified Facebook wall post bitching. There will never be another startup that turns into Genentech. The economics and non-organic growth drivers in biotech/pharma (you grow by buying new technology) is how you compete. Genentech was one of the first Biotechs when the only companies that could buy them back then didn't appreciate the promise of proteomics (Pfizer, Lilly, etc). Now, every big pharma is 'biopharma.'

Compared to Dendreon, Seattle Genetics, Pharmacyclics, Medivation, all these other companies that Genentech folks fled to, I see none that compare to Clovis (when you compare what those companies looked like pre-commercialization). Two breakthrough targeted therapies. No other company had that in their pipeline preapproval. They got Hoerter, Barnes, Hooks. Come on now. This isn't a "is Genentech better than Clovis or Clovis better than Genentech thing." its a "big company v small company" thing. And that's a personal decision based on what type of environment you want. Security v risk/reward (both financial and non-financial). Not which company you can overcharge more miles to you short sighted bitch.
 












Re: Genentech wouldn't buy Clovis comment. Clovis has a lung TKI that essentially works against the mutation (T790M) that causes Tarceva to fail some 70% of time. And Clovis drug is showing that it could work as well as Tarceva, if not better, in patients without that refractory mutation. That's Clovis product 1.

Clovis Product 2 is looking far better than Lymparza for Ovarian/BRCA. Genentech is so uninterested in this second product that we are essentially paying for combo trials with it and PDL-1.

Trust me, Genentech is very interested in Clovis. Freaking BA brings up Clovis as a threat to Tarceva at every QBR. My sense is, the big dogs here are waiting to see how Clovis Product 1 fairs against AZ's new lung TKI, as well as how the combo trial data starts looking for Clovis Product 2.

Listen, why can't these threads be more than just glorified Facebook wall post bitching. There will never be another startup that turns into Genentech. The economics and non-organic growth drivers in biotech/pharma (you grow by buying new technology) is how you compete. Genentech was one of the first Biotechs when the only companies that could buy them back then didn't appreciate the promise of proteomics (Pfizer, Lilly, etc). Now, every big pharma is 'biopharma.'

Compared to Dendreon, Seattle Genetics, Pharmacyclics, Medivation, all these other companies that Genentech folks fled to, I see none that compare to Clovis (when you compare what those companies looked like pre-commercialization). Two breakthrough targeted therapies. No other company had that in their pipeline preapproval. They got Hoerter, Barnes, Hooks. Come on now. This isn't a "is Genentech better than Clovis or Clovis better than Genentech thing." its a "big company v small company" thing. And that's a personal decision based on what type of environment you want. Security v risk/reward (both financial and non-financial). Not which company you can overcharge more miles to you short sighted bitch.


That's exactly why people leave GNE- to go to a smaller company. I could see Genentech swallowing Clovis depending on how the products do
 






You're spot on. Except for the quarter of a million in stock options payout I'd come back to Genentech with if Clovis is bought for the average M&A multiple in biotech the last three years. That $8k really should have factored into my decision, dumbass.

That's a BIG IF in terms of the buyout price and IF Genentech will take you back. After Uncle SAM takes his half of your options payout regardless of how much it is, you still have to find another job.

Good luck.
 






Does anyone understand that Avastin is an old product and, that with all the new products on the market, there will be some loss of business by attrition? OR, are there heads in the sand thinking growth will go on forever? We never have realistic conversations about what's going on in the market.


No one wants to have a realistic discussion because they will lose their power in the company. It's all about keeping their power because they can't jobs anywhere else….
 












I'm leaving because I have a bad manager. 3 others in my division tried but didn't get offers and one of them is a territory manager that my RSD loves. I hate to leave but it's to where you work, it's who you work for.
 






I'm leaving because I have a bad manager. 3 others in my division tried but didn't get offers and one of them is a territory manager that my RSD loves. I hate to leave but it's to where you work, it's who you work for.

I would agree with you. It's tough to stick it out with a bad manager haunting you. Good luck