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Anonymous
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You've conveniently never answered my question of why there is no electrolyte balance data in your package insert. The answer is because it didn't look good and Ironwood dumped it into the "on file" category. That's why it isn't safe for mice/young people. Your abortion non-sense will make you look like idiots in the near-term future when Amitiza gets approved for children! That's why we don't have a blackbox warning and you do. Don't worry. We'll let the GI's know why you got the blackbox warning.
I'm sure your peds indication for Amitiza will work out as well the Dexilant/Plavix message, or the Edarbyclor superiority data..LOL Typical Takeda jack-ass thinking, you guys have no idea on how to sell clinical and end up niching a small part of a market with a "safety" message.
Amitiza no electrolyte imbalance, okay that's great but the drug gives everyone nausea and barely works for an IBS patient. Why do all these "safety" patients and docs prefer Miralax? Not sold on the message!
Rozerem, your patients won't have to worry about slipping and falling in the middle of the night; no balance issues plus it's not addictive. Probably don't need to explain this one...or what about those COPD patients..LOL
Dexilant and Plavix; the latest and greatest hail mary of niching opportunities for Takeda. Docs don't care, they just write Nexium and Plavix and dose them 12 hours apart. GI's have been doing this for years.
Uloric; let's study it against 1/2 the allopurinol dose and then niche it for patients with renal impairment. Wow, another brilliant safety message from Takeda that didn't work.
Get me point? Keep drinking your Takeda cool-aid the way you are, Linzess will crush Amitiza sooner than anyone would have thought. I love the Takeda people. They sure know how to pound non-clinical messages down docs throats that noone cares about! Doesn't your company have about 10,000 bladder cancer lawsuits they need to worry about? I think the TZD class was where Takeda should have tried a "safety" message...LOL