Sharing clinical trial data: lessons from the YODA Project

Sharing data after a clinical trial has been completed seems like it should be a slam dunk, a win for many stakeholders, including the general public. Instead, such data sharing is still something of a hot-button issue, with critics questioning the capabilities and motives of those requesting the data, doubting the utility of replication analyses, and speculating that spurious safety findings would receive unwarranted attention and disrupt patient care.