Merck terminates Phase II trials for Alzheimer’s drug due to liver toxicity

MSD (Merck & Co) has voluntarily terminated two Phase II trials for MK-1942 due to potential liver toxicity due to the treatment.

The two Phase II trials (NCT05602727 and NCT04663321) were investigating MK-1942 as an adjunct treatment for mild to moderate Alzheimer’s disease and as an add-on therapy for treating major depressive disorder.