AbbVie's Rinvoq notches Crohn's disease win amid classwide JAK safety concerns

AbbVie's blockbuster hopeful Rinvoq notched a win in a tricky-to-treat group of Crohn's disease patients, potentially adding another arrow to the company's post-Humira quiver.

The JAK inhibitor helped a "significantly" greater proportion of patients achieve clinical remission and endoscopic response than placebo did, phase 3 data from the company's U-EXCEED study show. The trial studied the AbbVie drug in certain patients with moderate-to-severe Crohn's disease, and the results came after 12 weeks of treatment with the medicine or placebo.