Sadly, the closest thing to a blockbuster is dulaglutide (Trulicity). The data looked good, once a week dosing, even Novo admits that it is a good product. The GLP-1 field is unfortunately crowded and it will be tough to break into. The BI SGLT-2 drug may be good also . The rest of the pipeline is a complete joke, I am sorry to say. Lilly seems to pursue concepts others have long given up on, including the disastrous Alzheimer's drugs and the CETP inhibitor. The other companies seem to realize this: AZN managed to unload their worthless beta-secretase inhibitor on us...I am sure they are laughing themselves silly back in Sweden over that one. How is that for a serious reply?