Regeneron management was never 100% committed to Praluent when things got tough. Len was totally arrogant to think managed care companies would grab their ankles and take that price. Managed care stepped in and created the most difficult prior auth process and denial rate of any drug in last 10 years. The first year of launch 18% of scripts were approved and on average each one took extensive office staff time and each one was denied on average at least twice . There was never a problem with reps getting scripts. We had more scripts we knew what to do with but Lens HUB with 9 people working in day 1 to handle 320 reps from Sanofi and Regeneron made them behind 3 weeks 4 hours into the first day the HUB was operational..Anyone remember that Catwoman at Sanofi screeching at us that the Hub was waiting for our customers to call. PA's had to be faxed in (nothing electronic)- amazing in today's world and little things like fax line busy, or nobody keeping up putting paper in fax machines . We literally had 100's of scripts just disappear. Or the ridiculous contest they setup at launch just based on volume of scripts. Reps had offices send scripts in based on that they smoked or they were 10lbs overweight which further slowed process down but we rewarded reps with trips and accolades. Let's not forget about the cracker jack Sanofi PC team that got credit for every midlevel script (PA's and NP's) and some specialists. They were rewarded with bonuses and trips also for doing nothing. This was a complete mess. Len became less engaged and although Regeneron had done some shady patent dealings Len spent a fortune legally fighting Amgens claims for 3 years to only throw in the towel when Praluent finally started to win back share from Amgen after Praluent lost share during patent. Praluent reps were disregarded like trash in layoffs. A few escaped to Dupixent but the failure of Praluent falls squarely on Len.