- cafead May 23, 2023 at 11:42: AM
via Wave Life Sciences’ antisense oligonucleotide WVE-004 has come up short in a phase 1/2 trial. A year after Biogen and Ionis Pharmaceuticals killed off a similar asset, the biotech is waving goodbye to WVE-004 after getting a look at early-phase clinical trial data in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
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