I don’t believe there have been any head to head outcome studies, so you are speculating. Statins probably rank in the top five in significance of drug class discovery for the 20th century. I’m not saying Vascepta is bad, but to claim superiority over statins is a huge leap that has no scientific basis.
I agree! Vascepa is the clear winner.The Reduce it trials show Vescepa much better than statins....even when added to statins.
The 4S Trail with Zocor is the only placebo trial for outcomes in statins. After this trial the FDA would not allow placebo statin trials.
Main outcome of the 4S was:
1. 2,222 on Zocor or 2,222 on placebo
2. all pts had history of angina or MI
3. 5.4 year study
4. 182 deaths in zocor...256 deaths in placebo\
5. that's a 4% difference...not much
6.431 secondary events in Zocor....622 in Placebo
7. 19% vs 28%.
My take: this was the worse type pt. and NOT your reg. pts who have NOT had angina or MI.
Not a real big difference, but this type of pt. needs a station and Vascepa.
I would say ~85% of pts taking statins today do not fall in the area. IMHO
Vascepa a clear winner.....
Do not go into an office and make claims that vascepa is better than statins. Your cred will be shot immediately.
Go look up ASCOT...The Reduce it trials show Vescepa much better than statins....even when added to statins.
The 4S Trail with Zocor is the only placebo trial for outcomes in statins. After this trial the FDA would not allow placebo statin trials.
Main outcome of the 4S was:
1. 2,222 on Zocor or 2,222 on placebo
2. all pts had history of angina or MI
3. 5.4 year study
4. 182 deaths in zocor...256 deaths in placebo\
5. that's a 4% difference...not much
6.431 secondary events in Zocor....622 in Placebo
7. 19% vs 28%.
My take: this was the worse type pt. and NOT your reg. pts who have NOT had angina or MI.
Not a real big difference, but this type of pt. needs a station and Vascepa.
I would say ~85% of pts taking statins today do not fall in the area. IMHO
Vascepa a clear winner.....
Go look up ASCOT...
So, if a doc says I have many patients that can’t tolerate a statin, their trigs are above 150mg/dL , would you add Vascepa to their regimen because in the REDUCE-IT Trial those patients on even a low dose statin didn’t get any CV benefit? So what kind of CV benefit is there if a patient Is taking Vascepa monotherapy??Use your...SELLING...skills....After 28 years selling...this is HOW I would approach it:
Doctor look when "Vascepa " was added to a statin, look at the "additional" benefit on Vascepa has shown to prove better outcomes. Doctor, do you know of any other 'Lipid" drug when added to statin that shows this GREAT of a benefit??????
It's all in how you approach it. I launched Lipitor for PD and Crestor for AZ in 2003.
So, if a doc says I have many patients that can’t tolerate a statin, their trigs are above 150mg/dL , would you add Vascepa to their regimen because in the REDUCE-IT Trial those patients on even a low dose statin didn’t get any CV benefit? So what kind of CV benefit is there if a patient Is taking Vascepa monotherapy??
Maybe in our new detail piece it will highlight the decrease in CRP instead of us always having to pull out the PI. I truly believe we have one of the best lipid lowering meds. Especially when you consider no drug/drug interactions, costs, etc..FYI: I know about statins and have read many articles. They help very little. One doctor who wrote a book, said a patient may live 4 days longer on a statin. But, for pts. who have very high LDL and Trigs, I'm sure they help. But Vascepa, just by adding this drug to current drugs these pts. are taking it had a great effect.
Statins lower CRP, as does Vascepa, and many docs think this is where the good outcomes come from for most pts. I've studied these for over 20 years. Vascepa far better for most CAD pts. than statins. Fair Warning.
Maybe in our new detail piece it will highlight the decrease in CRP instead of us always having to pull out the PI. I truly believe we have one of the best lipid lowering meds. Especially when you consider no drug/drug interactions, costs, etc..
Maybe in our new detail piece it will highlight the decrease in CRP instead of us always having to pull out the PI. I truly believe we have one of the best lipid lowering meds. Especially when you consider no drug/drug interactions, costs, etc..
Maybe in our new detail piece it will highlight the decrease in CRP instead of us always having to pull out the PI. I truly believe we have one of the best lipid lowering meds. Especially when you consider no drug/drug interactions, costs, etc..
No outcomes data with a statin, and Lovasa not that good. In that case the docs would use LOPID...the first lipid drug by Parke-Davis....Helsinki Heart Trial, showed it better than placebo....many, many years ago. Lovasa in not used much for good reason.
I know about it...very rare...both drugs go thru the 3A4 isoenzyme. That's one reason Baycol was pulled off the market.....plus Lipitor also goes thru the same to a lesser effect. Zocor is made from a fungus. Crestor goes thru the 2C9 pathway.... Lopid still on market.lopid and a statin = rhabdomyolysis
do you forget your history that fast?
come on man!!
