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Takeda’s stem cell treatment Alofisel flunks phase 3 trial in Crohn's complication

cafead

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  • cafead   Oct 19, 2023 at 10:12: AM
via After trimming an early-stage Crohn’s disease candidate from its pipeline this year, Takeda is dealing with the failure of another of its therapies in a related indication.

Alofisel (daradstrocel), a stem cell therapy designed to treat one of the most debilitating complications of Crohn’s—complex perianal fistulas (CPF)—has come up short in a phase 3 trial.

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