Who is buffered from accountability for failed regulatory approvals? Usually it is the last people to touch the product submission before it is sent off (example. project team member). The problem with this is that the VPs and Directors are also calling the shots even if the their names and signatures are not directly on the final submission documents. Also people who work on the project in the early stages and then hand it off to the project teams usually are also buffered from accountability. So if they hand off something that is flawed the project team is accountable even if the product they were given for product submission is a flawed product.
What is amusing about this entire process is that if a product does not get approval it is the team members fault. But if the product does get approved the VPs, Directors and early stage researchers all come out of the woodwork and claim that their expertise is the reason for the approval. A reorganization should try to address this serious flaw in accountability here at B+L.