Question about Movantik

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anonymous

Guest
Movantik as we know is used for trauma patients or anyone prescribed an opiate drug for pain relief.

This opiate pain killer has a side effect of constipation.

Movantik is prescribed to reduce constipation, however it has an opiate as an active ingredient, now my question to you is why does movantik need to have a pain killer as an ingredient if the patient is already taking a pain killer?

I am not a DSI rep, however encountered your drug at one of the doctors offices while dropping my samples off.

Insight welcomed!
 






Movantik is a Mu opioid receptor antagonist. Thats why.

And trauma is no where to be seen in the indication. You were partly correct, Mo is indicated for patients who are on opioid therapy treating CHRONIC pain.

Precisely why Movantik is a niche drug with a very small market.

In order to "grow" the market, physicians will have to begin Rx'ing Mo for ANY opioid user, not just those taking opioids for the treatment of chronic pain. And that is why DSI will eventually get caught with their hands in the cookie jar as pressure mounts to increase both writers and # of Rx's per writer, on the "chosen few" who remain after the nuclear dust settles on Feb. 1, 2016.

Any way you slice it, Movantik is a niche drug in a very small market. Sure, opioids are the #1 prescribed prescription medication (very sad commentary on our society) in the world, but a small % are used to treat chronic pain.

I hope that answers your question, and I hope even more that you are not considering seeking employment with this pathetic company any time soon, that is, unless you are one of KK or RL's nieces or nephews whom they have promised jobs!!! Good luck!!!
 






anonymous said:
Movantik is a Mu opioid receptor antagonist. Thats why.

And trauma is no where to be seen in the indication. You were partly correct, Mo is indicated for patients who are on opioid therapy treating CHRONIC pain.

Precisely why Movantik is a niche drug with a very small market.

In order to "grow" the market, physicians will have to begin Rx'ing Mo for ANY opioid user, not just those taking opioids for the treatment of chronic pain. And that is why DSI will eventually get caught with their hands in the cookie jar as pressure mounts to increase both writers and # of Rx's per writer, on the "chosen few" who remain after the nuclear dust settles on Feb. 1, 2016.

Any way you slice it, Movantik is a niche drug in a very small market. Sure, opioids are the #1 prescribed prescription medication (very sad commentary on our society) in the world, but a small % are used to treat chronic pain.

I hope that answers your question, and I hope even more that you are not considering seeking employment with this pathetic company any time soon, that is, unless you are one of KK or RL's nieces or nephews whom they have promised jobs!!! Good luck!!!
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Thanks for replying,

Couldn't the doctor prescribe suboxone or naloxone to reverse the side effects of the opoid, perhaps a low dose as they are both opioid antagonists?
 






anonymous said:
Thanks for replying,

Couldn't the doctor prescribe suboxone or naloxone to reverse the side effects of the opoid, perhaps a low dose as they are both opioid antagonists?
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Look, if you're a patient, talk to your doctor. This isn't the place for medical advice. If you're anyone else, then piss off. We are all losing our jobs and this is a forum for employees to share updates and rip on senior leadership. Please stop posting here.
 






anonymous said:
Look, if you're a patient, talk to your doctor. This isn't the place for medical advice. If you're anyone else, then piss off. We are all losing our jobs and this is a forum for employees to share updates and rip on senior leadership. Please stop posting here.
Click to expand...

Listen up dick licker, who the fuck made you the voice of reason? If you don't have the answer to this post than carry you low grade pigeon brain IQ to another post.
 












Suboxone crosses the blood brain barrier and would interfere with the analgesic effect go the opioid.

Nlaxone is the movantik molecule, only difference is that the nalaxone molecule is pegylated to make Movantik so that it only binds with the Mu receptors in the gut (and other places in the body as well), and it does not cross the blood brain barrier so as to interfere with the analgesic effect of the opioid.

Hope that helps.
 






Just one more point to further add about Movantik:

Its basically a worthless POS drug serving a niche market. Considering the study was very much subjective with respect to bowel movements, definition of a very vague concept - constipation, and that the measureables were none other than a "patient bowel movement diary", yet only 46% were responders with placebo getting about a 32% responder rating, and in their 2nd study, Movantik beat placebo like 42% to 38%. I'm off a bit on these numbers (left the company 4 months ago), but nonetheless, the study is somewhat suspicious. To prove this point, the AZ and DSI product managers warned reps during training to "not get too deep in the clinical data".

WTF?!?!?! Nice drug KK and RL!!!
 






anonymous said:
Suboxone crosses the blood brain barrier and would interfere with the analgesic effect go the opioid.

Nlaxone is the movantik molecule, only difference is that the nalaxone molecule is pegylated to make Movantik so that it only binds with the Mu receptors in the gut (and other places in the body as well), and it does not cross the blood brain barrier so as to interfere with the analgesic effect of the opioid.

Hope that helps.
Click to expand...

Thanks for taking the time to explain, now i understand it.
 












anonymous said:
Just one more point to further add about Movantik:

Its basically a worthless POS drug serving a niche market. Considering the study was very much subjective with respect to bowel movements, definition of a very vague concept - constipation, and that the measureables were none other than a "patient bowel movement diary", yet only 46% were responders with placebo getting about a 32% responder rating, and in their 2nd study, Movantik beat placebo like 42% to 38%. I'm off a bit on these numbers (left the company 4 months ago), but nonetheless, the study is somewhat suspicious. To prove this point, the AZ and DSI product managers warned reps during training to "not get too deep in the clinical data".

WTF?!?!?! Nice drug KK and RL!!!
Click to expand...
 






So I had a doctor ask me about that stupid commercial and he said it made him think of sex toys. Me being the great sales person asked to clarify and he said that it looked like the lady was being followed by her two toned vibrator that had legs and arms. We both got a good laugh and whoops forgot to enter my P1 call.....
 






I'm a chronic pain patient and I started taking movsntik a few days ago.
It works great!!
Just need to decrease dosage if withdrawal symptoms are too intense.
By the way,
You are doing a great job alienating people. Was that your job at A/Z, or was it ass kissing?
Sounds like you have a case of "sour grapes" as the old adage says.
 












anonymous said:
I'm a chronic pain patient and I started taking movsntik a few days ago.
It works great!!
Just need to decrease dosage if withdrawal symptoms are too intense.
By the way,
You are doing a great job alienating people. Was that your job at A/Z, or was it ass kissing?
Sounds like you have a case of "sour grapes" as the old adage says.
Click to expand...
 






I took my first dose of Movantik today. I was surprised by how much it reversed the effects of my pain medication. My doctor mentioned some of her patients complained of pain due to the reversal of Movantik. Now I understand what she was/they were talking about. I'm taking opioids for pain caused by my surgical spinal fusion. Today I relived the surgery pain all over again!!
 












Question: I understand how Movantik is applied for use with opioid induced constipation. Is there also an application for constipation without opioid use? Are the same gut receptors affected with medications such as some that might be used to treat seizures?
 






anonymous said:
Question: I understand how Movantik is applied for use with opioid induced constipation. Is there also an application for constipation without opioid use? Are the same gut receptors affected with medications such as some that might be used to treat seizures?
Click to expand...
Talk to your doctor. It's never a good idea to get medical advice in this platform.
 












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