Joel Nowak and prostate cancer patients are beginning to understand Provenge sequencing. Joel is a Director at Malecare, a prostate cancer group, and moderator of "advancedprostatecancer" a members only web-board for prostate cancer patients. Things are turning positive for Provenge. See discussion from this board below:
http://health.groups.yahoo.com/group/advancedprostatecancer/message/16117
John,
I absolutely agree with you. As I have said, the moment I find out that I am castrate resistant is the moment I begin the arrangements to receive Provenge. As you said John if one waits and goes to Zytiga first there is a good possibility that you will never qualify for Provenge, however, taking Provenge will not exclude you from taking Zytiga in the future.
Joel
On Fri, Aug 10, 2012 at 7:36 PM, jjjnumbernine <jjjnumbernine@...> wrote:
Yes, that's exactly what I said. Johnson and Johnson kind of buried it in the press releases about Zytiga, but the Kaplan-Meier curves for the Zytiga group and the control group did not start to separate until 18 months--which was 4 months after the average 14 months of treatment ended. By that time, also, 20% of the men had already died--so there's a 1 in 5 chance a man will die before he gets any survival benefit from Zytiga.
Provenge survival benefit in all studies started after just 6 months.
Any man who qualifies for Provenge and doesn't get it asap is nuts. If you go with Zytiga first you might never get the benefit of Provenge, because more than minimal pain might come or you might be one of the 20% that dies before benefit. Provenge first--which only takes a month--means you keep the chance of getting benefit from both.
Easy decision. Provenge first.
Don't you agree, Joel?
John
http://health.groups.yahoo.com/group/advancedprostatecancer/message/16117
John,
I absolutely agree with you. As I have said, the moment I find out that I am castrate resistant is the moment I begin the arrangements to receive Provenge. As you said John if one waits and goes to Zytiga first there is a good possibility that you will never qualify for Provenge, however, taking Provenge will not exclude you from taking Zytiga in the future.
Joel
On Fri, Aug 10, 2012 at 7:36 PM, jjjnumbernine <jjjnumbernine@...> wrote:
Yes, that's exactly what I said. Johnson and Johnson kind of buried it in the press releases about Zytiga, but the Kaplan-Meier curves for the Zytiga group and the control group did not start to separate until 18 months--which was 4 months after the average 14 months of treatment ended. By that time, also, 20% of the men had already died--so there's a 1 in 5 chance a man will die before he gets any survival benefit from Zytiga.
Provenge survival benefit in all studies started after just 6 months.
Any man who qualifies for Provenge and doesn't get it asap is nuts. If you go with Zytiga first you might never get the benefit of Provenge, because more than minimal pain might come or you might be one of the 20% that dies before benefit. Provenge first--which only takes a month--means you keep the chance of getting benefit from both.
Easy decision. Provenge first.
Don't you agree, Joel?
John
