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Lexicon to disband sales team, lay off 60% of staff | BioPharma Dive
https://www.biopharmadive.com/news/lexicon-layoffs-restructuring-zynquista-deficiencies-fda/733712/
https://www.biopharmadive.com/news/lexicon-layoffs-restructuring-zynquista-deficiencies-fda/733712/
Dive Brief:
- Lexicon Pharmaceuticals will lay off 60% of its workforce and eliminate its commercial organization in a restructuring meant to save $100 million in operating costs next year.
- The shakeup follows Lexicon’s receipt of a letter from the Food and Drug Administration that cited “deficiencies” in the company’s approval application for its diabetes drug Zynquista. The therapy has been under review by the agency, which was aiming to reach a decision by Dec. 20.
- Lexicon will now pivot to focus on its research pipeline, which includes a drug in Phase 2 testing for diabetic peripheral neuropathic pain and a preclinical obesity therapy. The company is also testing sotagliflozin, the active ingredient of Zynquista, in a Phase 3 study of people with hypertrophic cardiomyopathy.