ITS TIME TO GO

Quote












How did Durso and company get it so wrong? What were they smoking to thing that this time would be different than the first CRL. Took the whole company down the drain! Durso, Michele and the FDA Regulatory guy should be fired!
 






anonymous said:
How did Durso and company get it so wrong? What were they smoking to thing that this time would be different than the first CRL. Took the whole company down the drain! Durso, Michele and the FDA Regulatory guy should be fired!
Click to expand...

What exactly did they get wrong? There was at least some reason to believe from the original data and frankly, the majority of costs for the program were already sunk, so why not try and move it forward? It's not as if Intercept has a rich pipeline to fall back on.
 






anonymous said:
What exactly did they get wrong? There was at least some reason to believe from the original data and frankly, the majority of costs for the program were already sunk, so why not try and move it forward? It's not as if Intercept has a rich pipeline to fall back on.
Click to expand...


FDA strongly suggesting we should wait for outcomes data before re-filing. They should have listened or turfed the program entirely because of the LDL and A1C signals. All of these things came out in the wash in the ad comm. The leaders knew, we didn't.

Tons of money and time went into re-reading those path slides. Oh well, hindsight it 20/20. Other companies will benefit from our learnings. Or, Lily will just make everyone skinny and there won't be NAFLD anymore.
 






anonymous said:
FDA strongly suggesting we should wait for outcomes data before re-filing. They should have listened or turfed the program entirely because of the LDL and A1C signals. All of these things came out in the wash in the ad comm. The leaders knew, we didn't.

Tons of money and time went into re-reading those path slides. Oh well, hindsight it 20/20. Other companies will benefit from our learnings. Or, Lily will just make everyone skinny and there won't be NAFLD anymore.
Click to expand...

Total BS, no reason to wait, they could always re-file with outcomes and investors aren't interested in waiting. Outcomes, LDL and A1C are not the issue, liver damage is the issue and there is NO way to address this issue. Yes additional $ went into re-reading, but minuscule in the context of the program and upside might have been worth it.
 






anonymous said:
Total BS, no reason to wait, they could always re-file with outcomes and investors aren't interested in waiting. Outcomes, LDL and A1C are not the issue, liver damage is the issue and there is NO way to address this issue. Yes additional $ went into re-reading, but minuscule in the context of the program and upside might have been worth it.
Click to expand...
And now, how many will be let go? 33per cent at least and some groups a whole lot more. That’s the damage Durso has wrought on the company and many lives. Saving the sales force because he needs them to get the PBC dollars before they disappear with the new PPARs. This company has nothing left and the worst management. He should be fired first!
 






The fact is, leadership wasn’t caught off-guard by FDA’s decision. For years, they’ve chosen to remain in their bubble and push out anyone who “spread negativity”. We’re left with the sycophants.
 






anonymous said:
And now, how many will be let go? 33per cent at least and some groups a whole lot more. That’s the damage Durso has wrought on the company and many lives. Saving the sales force because he needs them to get the PBC dollars before they disappear with the new PPARs. This company has nothing left and the worst management. He should be fired first!
Click to expand...

Fire him, but fire him because he hasn't pushed the company outside of FXR agonism, perhaps next gen will have a better profile, but in general, this class appears to be quite limited in potential.
 












anonymous said:
please keep him and his Sanofi cronies. They destroy every company they go to.
Click to expand...
Sad day today for the company. Letting all these people go for Durso’s and LR’s mistakes. They want PBC to be the driver with no new data since POISE! Shame on you Jerry. Hope you enjoy your fancy new house in NJ and your private toilet in the office! You can privately flush ICPT there without a single ounce of guilt!!
 






anonymous said:
Sad day today for the company. Letting all these people go for Durso’s and LR’s mistakes. They want PBC to be the driver with no new data since POISE! Shame on you Jerry. Hope you enjoy your fancy new house in NJ and your private toilet in the office! You can privately flush ICPT there without a single ounce of guilt!!
Click to expand...
Sunday Monday happy days
Tuesday Wednesday happy days
Thursday Friday happy days
Saturday what a day
Rockin' all week for you
 






anonymous said:
Sad day today for the company. Letting all these people go for Durso’s and LR’s mistakes. They want PBC to be the driver with no new data since POISE! Shame on you Jerry. Hope you enjoy your fancy new house in NJ and your private toilet in the office! You can privately flush ICPT there without a single ounce of guilt!!
Click to expand...

It’s almost like Sanofi is playing the long game since they can’t launch anything successfully. They promote incompetent misfits and cast them off to destroy the rest of the industry. Maybe if they destroy enough companies in the industry, they will look good by comparison.
 






anonymous said:
It’s almost like Sanofi is playing the long game since they can’t launch anything successfully. They promote incompetent misfits and cast them off to destroy the rest of the industry. Maybe if they destroy enough companies in the industry, they will look good by comparison.
Click to expand...

this is 100% correct and probably the most insightful thing I have ever read on CP. Sanofi was the first Island of Misfit Toys and when that place had their reckoning/ downsizing it was essentially a malignant tumor metastasizing throughout the industry scattering ill equipped, immature so-called leaders across the industry. Ask any Sanofi person about their time over there and they will all position themselves as the person singularly responsible for any and all successes that company had. It’s not an indictment of the company but rather the collection of insecure Peter-principled a-holes that seemed to find a home there. Our HR and Commercial leadership are just another branch in that rotted family tree.
 






























Top Bottom
Back
Quote