According to publically available information (Medscape), the AWP of a single-dose vial (180 mg) of Ilaris is priced at $19,000, while that for a single-dose vial (220 mg) of Arcalyst is priced at $6000. These costs are equivalent to $114,000 in annual cost of therapy for Ilaris (average dose of 150 mg [1 vial] q 8 weeks) vs $288,000 for Arcalyst (average dose of 160mg [1 vial] q 4 weeks); a difference of $174,000 per year.